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Full-Text Articles in Biomedical Engineering and Bioengineering
Comparison Of Whole-Head Functional Near-Infrared Spectroscopy With Functional Magnetic Resonance Imaging And Potential Application In Pediatric Neurology, Julie C. Wagner, Anthony Zinos, Wei-Liang Chen, Lisa Conant, Marsha Malloy, Joseph Heffernan, Brendan Quirk, Jeffrey Sugar, Robert W. Prost, Julian B. Whelan, Scott A. Beardsley, Harry T. Whelan
Comparison Of Whole-Head Functional Near-Infrared Spectroscopy With Functional Magnetic Resonance Imaging And Potential Application In Pediatric Neurology, Julie C. Wagner, Anthony Zinos, Wei-Liang Chen, Lisa Conant, Marsha Malloy, Joseph Heffernan, Brendan Quirk, Jeffrey Sugar, Robert W. Prost, Julian B. Whelan, Scott A. Beardsley, Harry T. Whelan
Biomedical Engineering Faculty Research and Publications
Background
Changes in cerebral blood flow in response to neuronal activation can be measured by time-dependent fluctuations in hemoglobin species within the brain; this is the basis of functional magnetic resonance imaging (fMRI) and functional near-infrared spectroscopy (fNIRS). There is a clinical need for portable neural imaging systems, such as fNIRS, to accommodate patients who are unable to tolerate an MR environment.
Objective
Our objective was to compare task-related full-head fNIRS and fMRI signals across cortical regions.
Methods
Eighteen healthy adults completed a same-day fNIRS-fMRI study, in which they performed right- and left-hand finger tapping tasks and a semantic-decision tones-decision …