Biomedical Engineering and Bioengineering Commons^™

Within-Subject Joint Independent Component Analysis Of Simultaneous Fmri/Erp In An Auditory Oddball Paradigm, Jain Mangalathu-Arumana, Scott A. Beardsley, E. Liebenthal

Biomedical Engineering Faculty Research and Publications

The integration of event-related potential (ERP) and functional magnetic resonance imaging (fMRI) can contribute to characterizing neural networks with high temporal and spatial resolution. This research aimed to determine the sensitivity and limitations of applying joint independent component analysis (jICA) within-subjects, for ERP and fMRI data collected simultaneously in a parametric auditory frequency oddball paradigm. In a group of 20 subjects, an increase in ERP peak amplitude ranging 1–8 μV in the time window of the P300 (350–700 ms), and a correlated increase in fMRI signal in a network of regions including the right superior temporal and supramarginal gyri, was …