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Full-Text Articles in Biomedical Engineering and Bioengineering
Repeatability Of In Vivo Parafoveal Cone Density And Spacing Measurements, Robert Garrioch, Christopher S. Langlo, Adam M. Dubis, Robert F. Cooper, Alfredo Dubra, Joseph Carroll
Repeatability Of In Vivo Parafoveal Cone Density And Spacing Measurements, Robert Garrioch, Christopher S. Langlo, Adam M. Dubis, Robert F. Cooper, Alfredo Dubra, Joseph Carroll
Biomedical Engineering Faculty Research and Publications
Purpose. To assess the repeatability and measurement error associated with cone density and nearest neighbor distance (NND) estimates in images of the parafoveal cone mosaic obtained with an adaptive optics scanning light ophthalmoscope (AOSLO).
Methods. Twenty-one participants with no known ocular pathology were recruited. Four retinal locations, approximately 0.65[degrees] eccentricity from the center of fixation, were imaged 10 times in randomized order with an AOSLO. Cone coordinates in each image were identified using an automated algorithm (with or without manual correction) from which cone density and NND were calculated. Owing to naturally occurring fixational instability, the 10 images recorded from …
Subclinical Photoreceptor Disruption In Response To Severe Head Trauma, Kimberly E. Stepien, Wanda M. Martinez, Adam M. Dubis, Robert F. Cooper, Alfredo Dubra, Joseph Carroll
Subclinical Photoreceptor Disruption In Response To Severe Head Trauma, Kimberly E. Stepien, Wanda M. Martinez, Adam M. Dubis, Robert F. Cooper, Alfredo Dubra, Joseph Carroll
Biomedical Engineering Faculty Research and Publications
Commotio retinae is a transient opacification of the retina due to outer retinal disruption occurring in a contrecoup fashion after blunt trauma.Histological studies in animals and humans after ocular blunt trauma have revealed that disruption occurs at the level of the photoreceptor outer segments and retinal pigment epithelium.Recent reports using optical coherence tomography (OCT) have shown detectable disruption at the level of the photoreceptor inner segment/outer segment junction and retinal pigment epithelium and that these changes may be reversible over time with restoration of normal outer retinal architecture.However, the resolution of existing OCT technology may not be sensitive enough to …