Biomedical Engineering and Bioengineering Commons^™

Study Of Upregulation Of Drug Resistance In H460 Lung Cancer Cells Via Microchannel Device, Nowmi Haider

Bioengineering Theses

Metastasis is the main reason of high mortality rates in cancer patients. Treating these patients becomes difficult once the cancer has metastasized, especially due to their drug resistance. Drug resistance is a common problem that occurs when treating cancer patients, as in most cancer types, the cells are capable of drug efflux. This makes treatments like chemotherapy ineffective. Therefore, it is important to find alternative methods of treatment that can effectively kill drug resistant cancer cells. Lung cancer is one type of cancer that is the second most diagnosed cancer in the U.S. In this study, microchannels were used to …