Biomedical Engineering and Bioengineering Commons^™

Design, Development, And Validation Of A Novel Optical Imaging Device For Biomedical Applications, Ashley Christine Dacy

Bioengineering Dissertations

Fluorescence and luminescence imaging are two promising optical techniques for diagnosing a variety of critical pathologies in vivo, including wound healing, inflammation, and vascular diseases. Despite this, there is a lack of imaging devices in research and commercially available that are capable of these imaging modalities in large animal applications. This work describes the progressive development of several optical imaging devices to fill this void, culminating in a final design with robust fluorescence and luminescence functionality designed for large animal and human applications. These devices are used to gather new data about various physical parameters in small and large animal …