Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Biomedical Engineering and Bioengineering
High-Resolution/High-Contrast Mri Of Human Articular Cartilage Lesions., Shadi F. Othman, Jun Li, Osama Abdullah, Jessy J. Moinnes, Richard L. Magin, Carol Muehleman
High-Resolution/High-Contrast Mri Of Human Articular Cartilage Lesions., Shadi F. Othman, Jun Li, Osama Abdullah, Jessy J. Moinnes, Richard L. Magin, Carol Muehleman
All Faculty Articles - School of Engineering and Computer Science
BACKGROUND: Magnetic resonance microscopy (MRM) is an important experimental tool in the identification of early cartilage lesions.
METHODS: Normal and degenerated cartilage samples were imaged at 11.74 T using a standard spin echo sequence. Quantitative MR measurements for T1, T2, and ADC were obtained and mapping for T2 and ADC was performed. The bi-exponential model for T2 relaxation was also explored. Histology was carried out for comparison with MR images.
RESULTS: MR images of cartilage samples displaying early stages of degeneration were positively correlated to their histological appearance in 23-microm high-resolution images and also with much shorter imaging times at …