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Full-Text Articles in Biomedical Engineering and Bioengineering
Early Biological Response Of Articular Cartilage To Hemiarthroplasty Wear, Debora Rossetti
Early Biological Response Of Articular Cartilage To Hemiarthroplasty Wear, Debora Rossetti
Electronic Thesis and Dissertation Repository
Hemiarthroplasties typically result in accelerated wear of the preserved side of the joint, resulting in suboptimal clinical outcomes and limited longevity. This in vitro study investigated the effects of hemiarthroplasty implant curvature on the early biological response of articular cartilage measured by proteoglycan release, histology, and surface morphology. Cartilage from boar radiocarpal joints were worn by metal pins of varying radii of curvature (RoC) using a pin-on-plate wear simulator. Histology and proteoglycan assays showed no significant differences between RoC treatment groups, and proteoglycan assays showed increased proteoglycan release 72 hours after wear testing in worn cartilage specimens compared to control …
The Effects Of A Porous Internal Lattice Design On The Articular Contact Mechanics Of Radial Head Hemiarthroplasty Implants, Jessica Benitah
The Effects Of A Porous Internal Lattice Design On The Articular Contact Mechanics Of Radial Head Hemiarthroplasty Implants, Jessica Benitah
Electronic Thesis and Dissertation Repository
Hemiarthroplasty, where one side of a joint is replaced, is a minimally invasive procedure. It allows for the preservation of native tissue, though a significant ramification is accelerated cartilage wear when articulating with high stiffness materials that do not mimic the mechanical stiffness of the native tissue. An implant that employs a lattice design can significantly lower the stiffness of a solid structure whilst maintaining strength. This study was conducted to investigate the effect of implementing a porous internal lattice structure with a thin outer shell on the articular contact mechanics, using a radial head hemiarthroplasty. It was hypothesized that …
The Efficacy Of Bionate As An Articulating Surface For Joint Hemiarthroplasty, Sarah Dedecker
The Efficacy Of Bionate As An Articulating Surface For Joint Hemiarthroplasty, Sarah Dedecker
Electronic Thesis and Dissertation Repository
Hemiarthroplasty procedures replace the diseased side of the joint with an implant to maximize bone preservation while maintaining more native anatomy than a total joint replacement. Even though hemiarthroplasty procedures have been clinically successful, they cause progressive cartilage damage over time due to the use of relatively stiff metallic implant materials. This work investigates the role of low moduli implant material on implant-cartilage contact mechanics and early in vitro cartilage wear. A finite element simulation was developed to assess the effect of low moduli implants in the range of 0.015-0.288 GPa on contact mechanics. Higher contact area and lower peak …
Effect Of Hemiarthroplasty Implant Contact Geometry And Material On Early Cartilage Wear, Alana Khayat
Effect Of Hemiarthroplasty Implant Contact Geometry And Material On Early Cartilage Wear, Alana Khayat
Electronic Thesis and Dissertation Repository
Hemiarthroplasty is a minimally invasive, cost-effective alternative to total arthroplasty in joints of the upper limb. Though these procedures reduce patient morbidity while restoring joint kinematics, their longevity is limited by wear of the adjacent cartilage. This work investigates the roles of contact geometry and implant stiffness on cartilage wear with the aim of elucidating the mechanics that contribute to cartilage damage. An in vitro study examined the influence of implant geometry on cartilage wear using a pin-on-plate wear simulator. A significant decrease in volumetric wear was observed as contact area increased, which suggests that maximizing contact area should be …