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Full-Text Articles in Biomedical Engineering and Bioengineering
Projection Effect Errors In Biomaterials And Bone Research, K. N. Bachus, R. D. Bloebaum
Projection Effect Errors In Biomaterials And Bone Research, K. N. Bachus, R. D. Bloebaum
Cells and Materials
Micoradiography and backscattered electron (BSE) imaging are techniques used to investigate the morphologic, histometric, and mineral content changes at the bone/biomaterials interface. Investigators have shown that the superimposition of multiple tissue layers can cause errors with both the morphologic observations and the histometric measurements of bone. The objective of this study was to document errors in the bone mineral content measurements associated with overlapping tissues.
Using a digital image analysis system, microradiographic and BSE images from canine cortical and cancellous bone were captured and analyzed. The results of this study showed that microradiography had more projection effect errors associated with …
Stereoscopic Analysis Of Trabecular Bone Orientation In Proximal Human Tibias, K. N. Bachus, M. K. Harman, R. D. Bloebaum
Stereoscopic Analysis Of Trabecular Bone Orientation In Proximal Human Tibias, K. N. Bachus, M. K. Harman, R. D. Bloebaum
Cells and Materials
The three-dimensional orientation of trabeculae is a key factor in determining the load carrying capabilities of cancellous bone. Previous biomechanical studies have shown that proximal tibias resected parallel to the articulating surface are stronger and stiffer than the contralateral tibias resected perpendicular to the long axis of the bone. However, morphologic evidence was not provided to help explain the mechanical differences.
To determine the orientation of the trabeculae in the medial condyle for both parallel cut and perpendicular cut specimens, a scanning electron microscope and stereoscopic techniques were used. Data showed that tibias cut parallel to the articular surface had …