Biomedical Engineering and Bioengineering Commons^™

Molecular Sensing And Imaging Of Human Disease Cells And Their Responses To Biochemical Stimuli, Lifu Xiao

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Advancement in microscopic and spectroscopic techniques could significantly improve our ability in the study and diagnosis of diseases. Especially, being able to image and detect human diseases at the cellular and molecular level allows people to diagnose diseases at early stages and to study the molecular mechanisms behind various diseases. Currently, histopathological techniques are most widely used for prognosis and diagnosis of human diseases. However, conventional histopathology requires a complex process of sample preparation, which limits the diagnostic efficiency of this technique. More importantly, it requires fixation of tissue or cell sample, making it unsuitable for the study of dynamic …