Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- Activities of daily living (1)
- Bayesian decoding (1)
- Bone Healing (1)
- Bone Mineral Density (1)
- Bone Regeneration (1)
-
- Convolutional Neural Networks (1)
- Deep Learning (1)
- Dynamics (1)
- Ehlers-Danlos Syndrome (1)
- Gait (1)
- Hidden Markov model (1)
- Hippocampus (1)
- Hydroxyapatite Phantom (1)
- Image Segmentation (1)
- Machine Learning (1)
- Machine learning (1)
- Medical Image Processing (1)
- MicroCT (1)
- Neuronal population code (1)
- Osteoblasts (1)
- P21 (1)
- Python (1)
- Regionprops (1)
- Shoulder (1)
- Spatial memory (1)
- Transformer (1)
- UC2288 (1)
Articles 1 - 5 of 5
Full-Text Articles in Biomedical Engineering and Bioengineering
Deciphering The Firing Patterns Of Hippocampal Neurons During Sharp-Wave Ripples, Kourosh Maboudi Ashmankamachali
Deciphering The Firing Patterns Of Hippocampal Neurons During Sharp-Wave Ripples, Kourosh Maboudi Ashmankamachali
Theses and Dissertations
The hippocampus is essential for learning and memory. Neurons in the rat hippocampus selectively fire when the animal is at specific locations - place fields - within an environment. Place fields corresponding to such place cells tile the entire environment, forming a stable spatial map supporting navigation and planning. Remarkably, the same place cells reactivate together outside of their place fields and in coincidence with sharp-wave ripples (SWRs) - dominant electrical field oscillations (150-250 Hz) in the hippocampus. These offline SWR events frequently occur during quiet wake periods in the middle of exploration and the follow-up slow-wave sleep and are …
Image-Based Cancer Diagnosis Using Novel Deep Neural Networks, Hosein Barzekar
Image-Based Cancer Diagnosis Using Novel Deep Neural Networks, Hosein Barzekar
Theses and Dissertations
Cancer is the major cause of death in many nations. This serious illness can only be effectivelytreated if it is diagnosed early. In contrast, biomedical imaging presents challenges to both clinical institutions and researchers. Physiological anomalies are often characterized by modest modifications in individual cells or tissues, making them difficult to detect visually. Physiological anomalies are often characterized by slight abnormalities in individual cells or tissues, making them difficult to detect visually. Traditionally, anomalies are diagnosed by radiologists and pathologists with extensive training. This procedure, however, demands the participation of professionals and incurs a substantial expense, making the classification of …
Python-Based Analysis To Segment Bone And Soft Tissue In A Healing Callus, Roberto Lopez
Python-Based Analysis To Segment Bone And Soft Tissue In A Healing Callus, Roberto Lopez
Theses and Dissertations
The main objective of this study was to produce a Python script that would help facilitate the segmentation process of both bone and soft tissue. The proposed script, in tangent with ImageJ and Mimics, was successful in producing viable results when the bone and soft tissue sample was placed near hydroxyapatite (HA) phantoms during the image acquisition process. It was important to acquire both the HA phantoms and the sample within the same image sequence as the script functioned by analyzing the statistical distribution of the different HA regions to locate the most ideal thresholding ranges to determine the bone …
Uc2288 Improves Osteogenic Capacity Of Murine Mesenchymal Stem Cells, Alisha Shaikh
Uc2288 Improves Osteogenic Capacity Of Murine Mesenchymal Stem Cells, Alisha Shaikh
Theses and Dissertations
The role of p21 is crucial in the cell cycle as it plays a diverse role in regulating it. Studies have demonstrated its role in proliferation, differentiation, apoptosis, and senescence. Inhibition of p21 has been shown to improve bone healing and regeneration after injury. UC2288 a cell-permeable molecule has been shown to inhibit p21. In this project we aim to assess the osteogenic capacity of UC2288. We tested the cytotoxicity of UC2288 with murine MSCs followed by culturing MSCs with UC2288 to test its capacity to differentiate into osteoblasts. Our results indicate that UC2288 increases MSC differentiation into osteoblasts as …
Full-Body Biomechanical Characterization Of Children With Hypermobile Ehlers-Danlos Syndrome During Gait And Activities Of Daily Living, Anahita Alahmoradiqashqai
Full-Body Biomechanical Characterization Of Children With Hypermobile Ehlers-Danlos Syndrome During Gait And Activities Of Daily Living, Anahita Alahmoradiqashqai
Theses and Dissertations
Hypermobile Ehlers-Danlos syndrome (hEDS) is an inherited connective tissue disorder, often under-diagnosed, and presenting with frequent chronic pain and severe musculoskeletal symptoms that can drastically reduce the quality of life during one’s life span. While there are limited quantitative approaches in the literature on adult movements, the biomechanics of movements during activities of daily living (ADLs) in children have not been investigated comprehensively. Therefore, the primary purpose of this dissertation was to characterize the biomechanics of the musculoskeletal system and investigate the biomechanics of hEDS by quantifying joint dynamics and muscle activations during ADLs and gait in the pediatric population. …