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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Engineering Bacterial Cellulose Scaffold And Its Biomimetic Composites For Bone And Cartilage Tissue Regeneration, Pelagie Marlene Favi
Engineering Bacterial Cellulose Scaffold And Its Biomimetic Composites For Bone And Cartilage Tissue Regeneration, Pelagie Marlene Favi
Doctoral Dissertations
A very promising approach to quickly and safely restore normal function to extensively damages and diseases bone and cartilage tissues is the regeneration of these injured tissues using an engineered support scaffold. This dissertation research focuses on the development and evaluation of native bacterial cellulose (BC) and chemically modified BCs as potential biomaterials for bone and cartilage regeneration using equine-derived bone marrow mesenchymal stem cells (EqMSCs).
The ability of native BC scaffold to maintain cell proliferation, viability, and in vitro differentiation of the seeded EqMSCs for application in bone and cartilage tissue engineering was studied. BC morphology was characterized using …
The Advancement Of Bacterial Cellulose As A Bone And Vascular Scaffolds, Ryan Lee Hammonds
The Advancement Of Bacterial Cellulose As A Bone And Vascular Scaffolds, Ryan Lee Hammonds
Doctoral Dissertations
Bacterial cellulose (BC) is a natural hydrogel made of nanofibers. This material has been used in commercial products, including wound dressings. BC can be modified and optimized for improved performance in multiple applications. This work will focus on producing and characterizing resorbable cellulose, a composite for bone applications, and a composite for a synthetic venous valve leaflet.
BC can be produced and modified to perform as a degradable tissue scaffold. This is achieved by an oxidation procedure after the initial production and purification of native BC. A material characterization of oxidized BC was performed to identify the changes in properties …