Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 4 of 4
Full-Text Articles in Biomedical Engineering and Bioengineering
Development And Implementation Of Telemetry Devices To Identify And Characterize Sources Of Intraocular Pressure Variability In Rats, Christina M. Nicou
Development And Implementation Of Telemetry Devices To Identify And Characterize Sources Of Intraocular Pressure Variability In Rats, Christina M. Nicou
USF Tampa Graduate Theses and Dissertations
Eye health depends partially on intraocular pressure (IOP) as abnormal levels can lead to ocular tissue damage. Glaucoma is a neurodegenerative disease that affects nearly 80 million people worldwide [1]. It is associated with elevated IOP, which can lead to irreversible blindness. Relatively little is known about IOP dynamics and the physiological factors that affect it as IOP is typically monitored using tonometry. Tonometry is a common tool used by clinicians and researchers to measure IOP noninvasively. It provides a good estimate of IOP mean but not variance because data collection takes time. Readings can also be influenced by subject …
Aqueous Humor Dynamics And Compound Action Potentials In The Anesthetized And Conscious Freely Moving Rat, Youssef Mohamed
Aqueous Humor Dynamics And Compound Action Potentials In The Anesthetized And Conscious Freely Moving Rat, Youssef Mohamed
USF Tampa Graduate Theses and Dissertations
Vision is dependent on the proper functioning of many intricate components of the eye. Aqueous humor dynamics function to keep the eye inflated at the right pressures and nourish avascular tissue in the eye while properties of the corneoscleral shell dictate how dynamic changes in volume and pressure affect tissue at the optic nerve head. Retinal ganglion cells exit the globe at the optic nerve head and carry all of the visual information to the brain for perception of visual stimulus. In this dissertation, we aim to present a lumped parameter model of the eye that can accurately describe the …
Aqueous Humor Dynamics And The Constant-Pressure Perfusion Model Of Experimental Glaucoma In Brown-Norway Rats, Kayla R. Ficarrotta
Aqueous Humor Dynamics And The Constant-Pressure Perfusion Model Of Experimental Glaucoma In Brown-Norway Rats, Kayla R. Ficarrotta
USF Tampa Graduate Theses and Dissertations
Glaucoma affects tens of millions of people and is the leading cause of irreversible blindness worldwide. Virtually all current glaucoma therapies target elevated intraocular pressure (IOP); however, the contribution of intracranial pressure (ICP) to glaucoma has recently garnered interest. Strain at the optic nerve head is now known to depend on the translaminar pressure difference (TLPD), which is the difference between IOP and ICP, rather than IOP alone. A better understanding of how IOP and ICP relate to glaucoma development and progression is essential for developing improved therapies and diagnostic tests. Glaucoma is commonly modeled in rats, yet aqueous humor …
Analysis And Processing Of Human Electroretinogram, Abdulrahman Mohammad Alaql
Analysis And Processing Of Human Electroretinogram, Abdulrahman Mohammad Alaql
USF Tampa Graduate Theses and Dissertations
Electroretinagram (ERG) is the recording of electrical activity of retinal cells elicited by light stimulation, which has been widely used to help diagnose different types of retinal dysfunctions. The ERG response signal is a short non-stationary signal that contains overlapping components. Different Digital Signal Processing (DSP) techniques are investigated using MATLAB to study the time-frequency responses of the ERG signal such as Short Time Fourier Transform (STFT), Continuous Wavelet Transform (CWT) and Discrete Wavelet Transform (DWT). The Photopic ERG signal was processed and analyzed in this thesis and the results of each technique have been investigated in detail. The Photopic …