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Full-Text Articles in Biomedical Engineering and Bioengineering

Bio-Desalination Of Brackish And Seawater Using Halophytic Algae, Endalkachew Sahle-Demessie, Ashraf Aly Hassan, Amro El Badawy May 2019

Bio-Desalination Of Brackish And Seawater Using Halophytic Algae, Endalkachew Sahle-Demessie, Ashraf Aly Hassan, Amro El Badawy

Department of Civil and Environmental Engineering: Faculty Publications

Global demand for water is rising. A sustainable and energy efficient approach is needed to desalinate brackish sources for agricultural and municipal water use. Genetic variation among two algae species, Scenedesmus species (S. sp.) and Chlorella vulgaris (C. vulgaris), in their tolerance and uptake of salt (NaCl) was examined for potential bio-desalination of brackish water. Salt-tolerant hyper-accumulators were evaluated in a batch photobioreactors over salinity concentration ranging from 2 g/L to 20 g/L and different nutrient composition for their growth rate and salt-uptake. During algae growth phase, the doubling time varied between 0.63 and 1.81 days for S …


Advanced Selection Methodologies For Dnazymes In Sensing And Healthcare Applications, Sandeep Kumar, Shikha Jain, Neeraj Dilbaghi, Amrik Singh Ahluwalia, Ashraf Aly Hassan, Ki-Hyun Kim Mar 2019

Advanced Selection Methodologies For Dnazymes In Sensing And Healthcare Applications, Sandeep Kumar, Shikha Jain, Neeraj Dilbaghi, Amrik Singh Ahluwalia, Ashraf Aly Hassan, Ki-Hyun Kim

Department of Civil and Environmental Engineering: Faculty Publications

DNAzymes have been widely explored owing to their excellent catalytic activity in a broad range of applications, notably in sensing and biomedical devices. These newly discovered applications have built high hopes for designing novel catalytic DNAzymes. However, the selection of efficient DNAzymes is a challenging process but one that is of crucial importance. Initially, systemic evolution of ligands by exponential enrichment (SELEX) was a labor-intensive and time-consuming process, but recent advances have accelerated the automated generation of DNAzyme molecules. This review summarizes recent advances in SELEX that improve the affinity and specificity of DNAzymes. The thriving generation of new DNAzymes …