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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Advanced Selection Methodologies For Dnazymes In Sensing And Healthcare Applications, Sandeep Kumar, Shikha Jain, Neeraj Dilbaghi, Amrik Singh Ahluwalia, Ashraf Aly Hassan, Ki-Hyun Kim
Advanced Selection Methodologies For Dnazymes In Sensing And Healthcare Applications, Sandeep Kumar, Shikha Jain, Neeraj Dilbaghi, Amrik Singh Ahluwalia, Ashraf Aly Hassan, Ki-Hyun Kim
Department of Civil and Environmental Engineering: Faculty Publications
DNAzymes have been widely explored owing to their excellent catalytic activity in a broad range of applications, notably in sensing and biomedical devices. These newly discovered applications have built high hopes for designing novel catalytic DNAzymes. However, the selection of efficient DNAzymes is a challenging process but one that is of crucial importance. Initially, systemic evolution of ligands by exponential enrichment (SELEX) was a labor-intensive and time-consuming process, but recent advances have accelerated the automated generation of DNAzyme molecules. This review summarizes recent advances in SELEX that improve the affinity and specificity of DNAzymes. The thriving generation of new DNAzymes …
Investigation Of Bovine Serum Albumin (Bsa) Attachment Onto Self-Assembled Monolayers (Sams) Using Combinatorial Quartz Crystal Microbalance With Dissipation (Qcm-D) And Spectroscopic Ellipsometry (Se), Hanh T.M. Phan, Shannon L. Bartelt-Hunt, Keith B. Rodenhausen, Mathias Schubert, Jason C. Bartz
Investigation Of Bovine Serum Albumin (Bsa) Attachment Onto Self-Assembled Monolayers (Sams) Using Combinatorial Quartz Crystal Microbalance With Dissipation (Qcm-D) And Spectroscopic Ellipsometry (Se), Hanh T.M. Phan, Shannon L. Bartelt-Hunt, Keith B. Rodenhausen, Mathias Schubert, Jason C. Bartz
Department of Civil and Environmental Engineering: Faculty Publications
Understanding protein adsorption kinetics to surfaces is of importance for various environmental and biomedical applications. Adsorption of bovine serum albumin to various selfassembled monolayer surfaces including neutral and charged hydrophilic and hydrophobic surfaces was investigated using in-situ combinatorial quartz crystal microbalance with dissipation and spectroscopic ellipsometry. Adsorption of bovine serum albumin varied as a function of surface properties, bovine serum albumin concentration and pH value. Charged surfaces exhibited a greater quantity of bovine serum albumin adsorption, a larger bovine serum albumin layer thickness, and increased density of bovine serum albumin protein compared to neutral surfaces at neutral pH value. The …