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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Understanding The Development Of Infant Feeding: A Spectral Analysis Approach, Pooja Vijaygopal
Understanding The Development Of Infant Feeding: A Spectral Analysis Approach, Pooja Vijaygopal
University of Kentucky Master's Theses
Feeding problems in preterm neonates stem from complications of early delivery. Attainment of independent feeding is a prerequisite for Neonatal Intensive Care Unit (NICU) discharges. Some quantitative studies of infant feeding involve excessive amounts of time for data processing. Multivariate spectral analysis was used to minimize time for investigation of variability in these rhythms. Auto and Cross-spectral parameters of the rhythms were correlated with Gestational Age (GA), Postmenstrual Age (PMA), Birthweight (BW), Days of Life (DOL), and Time Since First Nipple feeding (TSFN). Auto-spectral analysis showed 25.55% increase in Bandwidth of suck (bw-su) for a 2-week increase in GA (DOL …
Regeneration Of Damaged Growth Plate Using Igf-I Plasmid-Releasing Porous Plga Scaffolds, Nirmal Ravi
Regeneration Of Damaged Growth Plate Using Igf-I Plasmid-Releasing Porous Plga Scaffolds, Nirmal Ravi
University of Kentucky Doctoral Dissertations
Growth plate injuries account for 15-30% of long bone fractures in children. About 10% of these result in significant growth disturbances due to formation of a boney bar. If not treated correctly, this can lead to life-lasting consequences of limb length inequalities and angular deformities. Current treatments for growth plate injuries include removal of boney bar and insertion of fat, silicone, bone cement, etc.. This treatment y is inadequate, leaving almost half of these patients with continued deformities. This dissertation reports characterization of a DNA–containing porous poly(lactic-co-glycolic acid) (PLGA) scaffold system, chondrogenesis using insulin-like growth factor I (IGF-I) plasmid-releasing scaffolds …
Effects Of Calcium Changes On Hysteresis In Restitution Of Action Potential Duration, Kathleen Marie Guzman
Effects Of Calcium Changes On Hysteresis In Restitution Of Action Potential Duration, Kathleen Marie Guzman
University of Kentucky Master's Theses
Sudden cardiac death (SCD) is a leading cause of fatalities. Several methods have been developed to predict instability in myocytes which could lead to SCD. The focus of this study was on altering memory in myocytes, i.e. hysteresis in restitution of action potential duration (APD), by differing levels of calcium. Determination of alteration was implemented by using a diastolic interval (DI) control program that implements a sinusoidal change in DI. Plotting APD versus previous DI, i.e. restitution, produces a hysteresis loop. From these hysteresis loops, five parameters were used to determine measures of memory: area, thickness, overall tilt, max delay …