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Full-Text Articles in Biomedical Engineering and Bioengineering
Microsphere Spray System For Wound Coverage, Nicholas J. Andersen
Microsphere Spray System For Wound Coverage, Nicholas J. Andersen
Theses and Dissertations--Biomedical Engineering
Spinal fusion is used to treat diseases or disorders of the spine by fusing together two or more vertebrae. Two associated risks with spinal fusion are infection and blood loss. Administration of tranexamic acid is used to prevent blood loss, and transfusions are given following blood loss. Surgical site infections are prevented with vancomycin powder spread into the surgical wound, while established infections are treated by debridement and delivery of antibiotics for 4 to 6 weeks. The present research explored an alternate method to prevent and treat blood loss or infection in spinal fusion. Poly(lactic-co-glycolic acid) (PLGA) microspheres was used …
Magnesium-Titanium Alloys For Biomedical Applications, Ilona Hoffmann
Magnesium-Titanium Alloys For Biomedical Applications, Ilona Hoffmann
Theses and Dissertations--Chemical and Materials Engineering
Magnesium has been identified as a promising biodegradable implant material because it does not cause systemic toxicity and can reduce stress shielding. However, it corrodes too quickly in the body. Titanium, which is already used ubiquitously for implants, was chosen as the alloying element because of its proven biocompatibility and corrosion resistance in physiological environments. Thus, alloying magnesium with titanium is expected to improve the corrosion resistance of magnesium.
Mg-Ti alloys with a titanium content ranging from 5 to 35 at.-% were successfully synthesized by mechanical alloying. Spark plasma sintering was identified as a processing route to consolidate the alloy …