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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Computational Methodology For Generating Patient-Specific Soft Tissue Representations, Ahilan Anantha Krishnan
Computational Methodology For Generating Patient-Specific Soft Tissue Representations, Ahilan Anantha Krishnan
Electronic Theses and Dissertations
This dissertation focused on modeling specimen-specific soft tissue structures in the context of joint replacement surgery. The research addressed four key aspects. The first study involved developing a workflow for creating finite element models of the hip capsule to replicate its torque-rotational response. Experimental data from ten cadaveric hips were used to calibrate the models, resulting in improved accuracy and relevance for surgical planning and implant design. The second study tackled the challenge of expediting the calibration of mechanical properties of the hip capsule to match patient-specific laxities. A statistical shape function model was proposed to generate patient-specific finite element …
Effects On Initial Fixation Of Cementless Tibial Trays In Total Knee Arthroplasty, Brooke Fritts Thompson
Effects On Initial Fixation Of Cementless Tibial Trays In Total Knee Arthroplasty, Brooke Fritts Thompson
Electronic Theses and Dissertations
Bone mineral density (BMD), among other factors, largely effect the initial stability of the cementless tibial tray component in a total knee replacement (TKR), where increased motion at the tray-bone interface hinders bony ingrowth. With a lack of bony ingrowth, the cementless implant will not experience long-term success. Understanding which factors influence initial stability yields insight into surgical technique considerations and help inform a surgeon’s implant choice. The objective of this study was to evaluate factors influencing the initial stability of cementless tibial trays using a 6-degree of freedom (6-DOF) robotic joint simulator, the AMTI VIVO, and combined loading scenarios …
The Relative Contribution Of Fixation Features, Activity, And Tibiofemoral Conformity On Initial Stability Of Cementless Tibial Trays, James Sullivan Deacy
The Relative Contribution Of Fixation Features, Activity, And Tibiofemoral Conformity On Initial Stability Of Cementless Tibial Trays, James Sullivan Deacy
Electronic Theses and Dissertations
Initial stability of cementless total knee replacements (TKR) is critical to implant success as excessive motion between the bone and implant prevents bony ingrowth that is critical to the long-term survivability of cementless implants. Prior studies have shown that excessive micromotion causes fibrous tissue growth instead of beneficial bony growth. There are many factors that influence initial stability including the design of the tibial tray and the tibiofemoral articulations. Understanding the impacts of these design features on micromotion between the bone and implants is crucial to improving the performance of cementless TKR. Prior studies only tested for the effect of …
Computational Biomechanical Modeling Of The Human Knee During Kneeling, Tariq R. Abo-Alhol
Computational Biomechanical Modeling Of The Human Knee During Kneeling, Tariq R. Abo-Alhol
Electronic Theses and Dissertations
Total knee replacement benefits patients who suffer from severe knee pain or joint stiffness and other joint related illnesses that limit everyday activities. There has been an increase in the number of procedures performed each year and a need to evaluate the performance of these implants during specialized activities such as kneeling. Most computational studies lack insight into inter-patient variability and the results do not apply to large population. This study developed: (1) three-dimensional explicit finite element (FE) models to investigate natural and implanted knee joint kinematics and bone strain and (2) a platform to enable population-based evaluation by combining …