Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Bioreactor (1)
- Bug Units (1)
- BugEye (1)
- COMSOL (1)
- Cell environment (1)
-
- Cell survival (1)
- Cell-based therapy (1)
- Dissipative Particle Dynamics (DPD) (1)
- Fermentation (1)
- Fluids (1)
- Hemofiltration (1)
- Hemolysis (1)
- Meloxicam (1)
- Membrane filtration (1)
- Microneedle patches (1)
- N-methyl-2-pyrrolidone (NMP) (1)
- Optical density (1)
- Pain management (1)
- Polyethersulfone (PES) (1)
- Polymer science (1)
- Polyvinyl alcohol (1)
- S. cerevisiae (1)
- Shear-stress (1)
- Simulation (1)
- Transdermal drug delivery (1)
Articles 1 - 5 of 5
Full-Text Articles in Biomedical Engineering and Bioengineering
Dpd Guided Insight On The Formation Process Of Polyethersulfone Membranes By Nonsolvent Induced Phase Separation And The Effects Of Additives, Eric Ledieu
Graduate Theses and Dissertations
Dissipative particle dynamics (DPD), a coarse grain simulation method, was applied to the membrane formation process of non-solvent induced phase separation (NIPS) to gain further insight on the mechanism of certain variables and how they affect the final morphology. NIPS involves two solutions, an organic polymer dissolved in an organic solvent colloquially called the dope and an aqueous coagulation bath, brought into contact with one another. The solvents then mix, causing the polymer to fall out of solution as an asymmetric membrane with a dense surface layer and a more open subsurface layer in response to the decreasing solubility. Polyethersulfone …
Polymeric Biomaterials Approaches For Engineering The In Vitro Cellular Microenvironment For Mscs, Mahsa Letter-Mahsa Haseli
Polymeric Biomaterials Approaches For Engineering The In Vitro Cellular Microenvironment For Mscs, Mahsa Letter-Mahsa Haseli
Graduate Theses and Dissertations
Cell therapy is a technology that relies on replacing diseased or dysfunctional cells with healthy functioning ones. One of the cells used for such advanced therapies are stem cells, owing to their ability to differentiate into specific cells required for repairing damaged or defective tissues or cells. The majority of cell-based products are intended to transiently persist in the patient, secreting factors which then allow the patient’s body to heal; in these products, the cells are subsequently eliminated from the body. Furthermore, unique manufacturing platforms, in addition to novel commercialization strategies, will be required to create a successful, sustainable cell …
A Comparison Of Optical Measurement Methods For The Growth Of S. Cerevisiae, Jackson Black
A Comparison Of Optical Measurement Methods For The Growth Of S. Cerevisiae, Jackson Black
Chemical Engineering Undergraduate Honors Theses
Genetic engineering of living organisms provides the opportunity to express and harvest different proteins from cell surfaces. Yeast (S. cerevisiae) is one such organism and is capable of being grown on an industrial scale. Cellular concentration is an important parameter to monitor while fermentation processes are underway, in order to control the environment inside the growth medium and maximize yields. Spectrophotometry is a conventional method for measuring concentration, but is limited by a narrow absorbance range, and the need for on-site periodic sampling. A continuous method of measurement, as provided by Bug Labs BE2100 non-invasive biomass monitor, would …
Characterizing And Quantifying Shear-Induced Hemolysis In A Hollow Fiber Membrane System, Siddhi Bhat
Characterizing And Quantifying Shear-Induced Hemolysis In A Hollow Fiber Membrane System, Siddhi Bhat
Chemical Engineering Undergraduate Honors Theses
Clinical studies have shown that patients undergoing renal replacement therapy are more susceptible to developing hemolysis, or the rupturing of red blood cells. Rapid hemolysis can cause symptoms such as anorexia, vomiting, and even death in severe cases. The aim of this study is to identify how shear stress within a hollow fiber membrane impacts the level of hemolysis that occurs. This allows for the optimization of the ultrafiltration membranes that are typically used for hemofiltration treatments. The variables being studied are the radii of hollow fibers, number of fibers, and volumetric flow rate of blood being circulated. Here, we …
Comparing Firocoxib And Meloxicam In The Application Of Microneedle Patch For Transdermal Drug Delivery, Ruohan Li
Chemical Engineering Undergraduate Honors Theses
This thesis compares the performance of meloxicam and firocoxib in the aspects of its physical characteristic, chemical compositions, and in-vitro performances for transdermal pain management microneedle patches on farm animals. The microneedle patches are composed of polyvinyl alcohol (PVA), type I collagen (COL), and chitosan (CHI) as base material that carries NSAIDs to achieve therapeutic purposes. Scanning electron microscopy (SEM) was utilized to observe the morphological and physical characteristics of the microneedle patches. Both meloxicam and firocoxib microneedle patches were successfully prepared using the methodology, with organized microneedle distribution and sizing. And Fourier transform infrared spectroscopy (FTIR) confirmed the chemical …