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Full-Text Articles in Biomedical Engineering and Bioengineering

Hierarchical Based Classifcation Method Based On Fusion Ofgaussian Map Descriptors Foralzheimer Diagnosis Using T1‑Weighted Magnetic Resonance Imaging, Nourhan Zayed, Shereen E. Morsy, Inas A. Yassine Aug 2023

Hierarchical Based Classifcation Method Based On Fusion Ofgaussian Map Descriptors Foralzheimer Diagnosis Using T1‑Weighted Magnetic Resonance Imaging, Nourhan Zayed, Shereen E. Morsy, Inas A. Yassine

Mechanical Engineering

Alzheimer’s disease (AD) is considered one of the most spouting elderly diseases. In 2015, AD is reported the US’s sixth cause of death. Substantially, non-invasive imaging is widely employed to provide biomarkers supporting AD screening, diagnosis, and progression. In this study, Gaussian descriptors-based features are proposed to be efcient new biomarkers using Magnetic Resonance Imaging (MRI) T1-weighted images to diferentiate between Alzheimer’s disease (AD), Mild Cognitive Impairment (MCI), and Normal controls (NC). Several Gaussian map-based features are extracted such as Gaussian shape operator, Gaussian curvature, and mean curvature. The aforementioned features are then introduced to the Support Vector Machine (SVM). …


A Review Of 3d Polymeric Scaffolds For Bone Tissue Engineering: Principles, Fabrication Techniques, Immunomodulatory Roles, And Challenges, Hassan Nageh, Ahmed G. Abdelaziz, Sara M. Abdo, Mohga S. Abdalla, Asmaa A. Amer, Abdalla Abdal-Hay, Ahmed Barhoum Feb 2023

A Review Of 3d Polymeric Scaffolds For Bone Tissue Engineering: Principles, Fabrication Techniques, Immunomodulatory Roles, And Challenges, Hassan Nageh, Ahmed G. Abdelaziz, Sara M. Abdo, Mohga S. Abdalla, Asmaa A. Amer, Abdalla Abdal-Hay, Ahmed Barhoum

Nanotechnology Research Centre

Over the last few years, biopolymers have attracted great interest in tissue engineering and regenerative medicine due to the great diversity of their chemical, mechanical, and physical properties for the fabrication of 3D scaffolds. This review is devoted to recent advances in synthetic and natural polymeric 3D scaffolds for bone tissue engineering (BTE) and regenerative therapies. The review comprehensively discusses the implications of biological macromolecules, structure, and composition of polymeric scaffolds used in BTE. Various approaches to fabricating 3D BTE scaffolds are discussed, including solvent casting and particle leaching, freeze-drying, thermally induced phase separation, gas foaming, electrospinning, and sol–gel techniques. …