Biomedical Engineering and Bioengineering Commons^™

Antimicrobial Susceptibility Of P. Aeruginosa Clinical Isolates, Tian Gao

Theses - ALL

Long-term infection caused by P. aeruginosa poses a major threat to personal and public health, and causes billions of dollars in medical expenses. To develop more effective controls, it is important to accurately evaluate antibiotic susceptibility of clinical isolates and understand how susceptibility changes during the course of infection. Conventional drug susceptibility tests using nutrient-rich media have been questioned regarding their relevance due to the difference between the model in vivo test conditions and the environment in the patients. Here, we report that 27 clinical strains of P. aeruginosa isolated from cystic fibrosis patients showed higher drug resistance in Artificial …