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Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
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- Life Sciences (37)
- Biomedical Devices and Instrumentation (31)
- Biological Engineering (29)
- Molecular, Cellular, and Tissue Engineering (28)
- Medicine and Health Sciences (27)
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- Bioelectrical and Neuroengineering (21)
- Bioimaging and Biomedical Optics (17)
- Biomaterials (16)
- Vision Science (16)
- Neuroscience and Neurobiology (13)
- Mechanical Engineering (11)
- Biochemistry, Biophysics, and Structural Biology (10)
- Electrical and Computer Engineering (10)
- Biotechnology (9)
- Computational Neuroscience (9)
- Materials Science and Engineering (9)
- Biomechanics and Biotransport (8)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (7)
- Biochemistry (7)
- Biology and Biomimetic Materials (7)
- Biomechanical Engineering (7)
- Biomedical (7)
- Chemical Engineering (7)
- Other Biomedical Engineering and Bioengineering (7)
- Cell and Developmental Biology (6)
- Bioresource and Agricultural Engineering (5)
- Medical Sciences (5)
- Nanoscience and Nanotechnology (5)
- Keyword
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- Cancer (5)
- Ultrasound (5)
- Tissue engineering (4)
- Aneurysm (3)
- Angiotensin II (3)
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- Aorta (3)
- Biomechanics (3)
- Biosensor (3)
- Biotechnology (3)
- Imaging (3)
- Metastasis (3)
- Microfluidics (3)
- Regenerative engineering (3)
- Scaffolds (3)
- Yeast (3)
- Aneurysms (2)
- Biomedical (2)
- Bioreactor (2)
- Biosensors (2)
- Breast cancer (2)
- Collagen (2)
- Differentiation (2)
- Elastase (2)
- Embryo (2)
- Extracellular Matrix (2)
- Extracellular matrix (2)
- Fabrication (2)
- Hydrocephalus (2)
- Hydrogels (2)
- Hydrogen peroxide (2)
- Publication Year
- Publication
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- The Summer Undergraduate Research Fellowship (SURF) Symposium (127)
- MODVIS Workshop (15)
- Graduate Industrial Research Symposium (3)
- Ideas: Exhibit Catalog for the Honors College Visiting Scholars Series (3)
- The 8th International Conference on Physical and Numerical Simulation of Materials Processing (2)
Articles 1 - 30 of 152
Full-Text Articles in Biomedical Engineering and Bioengineering
Sea-Phages Course-Based Undergraduate Research Experience For Creating A Biotechnology Workforce Development Pipeline, Daphne Fauber, Kari Clase, Carol Weaver
Sea-Phages Course-Based Undergraduate Research Experience For Creating A Biotechnology Workforce Development Pipeline, Daphne Fauber, Kari Clase, Carol Weaver
Graduate Industrial Research Symposium
Purdue University has been a member of the SEA-PHAGES (Science Education Alliance-Phage Hunters Advancing Genomics and Evolutionary Science) program since 2011. This program, created in conjunction with the Howard Hughes Medical Institute (HHMI), facilitates undergraduate curriculum for the authentic discovery of novel bacteriophages within the classroom. Since joining the program, undergraduates at Purdue have harnessed wet lab and bioinformatics principles to contribute over 200 previously uncharacterized bacteriophages and 25 novel genomes to the wider scientific literature. The SEA-PHAGES classes at Purdue have resulted in tangible professional deliverables for students through conference presentations and publications. Student outcomes also include transferable skills …
Raman Spectroscopy - An Analytical Tool For Biologics, Cindy Mayorga, Shreya Milind Athalye, Mohit Verma
Raman Spectroscopy - An Analytical Tool For Biologics, Cindy Mayorga, Shreya Milind Athalye, Mohit Verma
Graduate Industrial Research Symposium
Raman Spectroscopy (RS) is a non-invasive technique that analyses biomolecules qualitatively and quantitatively. Raman spectroscopy measures the inelastic scattering of light due to molecular vibrations. It can be applied to liquid, solid, or semi-solid forms of the biological sample reducing the sample preparation measures. The minimal sample preparation and non-invasive nature of Raman Spectroscopy can be applied in developing a Process analytical technology (PAT) tool and as a diagnostic tool. We demonstrated qualitative and quantitative measurements of biologics with Raman spectroscopy through our previous studies. Our results indicate that RS distinguishes various Gram-positive and Gram-negative bacteria, fungi, and a mixture …
The Next-Gen Crop Nutrient Stress Identification With High-Precision Sensing Technology In Digital Agriculture, Zhihang Song, Ziling Chen, Xing Wei, Jian Jin
The Next-Gen Crop Nutrient Stress Identification With High-Precision Sensing Technology In Digital Agriculture, Zhihang Song, Ziling Chen, Xing Wei, Jian Jin
Graduate Industrial Research Symposium
Crop yields are facing significant losses from nutrient deficiencies. Over-fertilizing also has negative economic and environmental impacts. It is challenging to optimize fertilizing without an accurate diagnosis. Recently, plant phenotyping has demonstrated outstanding capabilities in estimating crop traits. As one of the leading technologies, LeafSpec, provides high-quality crop image data for improving phenotyping quality. In this study, novel algorithms are developed for LeafSpec to identify crop nutrient deficiencies more accurately. Combined with UAV system, this technology will bring growers a robust solution for fertilizing diagnosis and scientific crop management.
Scandy: Simulating Realistic Human Scanpaths In Dynamic Real-World Scenes, Nicolas Roth, Martin Rolfs, Klaus Obermayer
Scandy: Simulating Realistic Human Scanpaths In Dynamic Real-World Scenes, Nicolas Roth, Martin Rolfs, Klaus Obermayer
MODVIS Workshop
No abstract provided.
A Note From The Co-Editors, Jada C. Johnson
A Note From The Co-Editors, Jada C. Johnson
Ideas: Exhibit Catalog for the Honors College Visiting Scholars Series
An introduction to the fifth issue of the third volume of Ideas Magazine, concerning the thoughts, experience, and work of Dr. Marcelo J.S. de Lemos.
A Note From The Editor, Daphne Fauber
A Note From The Editor, Daphne Fauber
Ideas: Exhibit Catalog for the Honors College Visiting Scholars Series
This piece is a letter from Daphne Fauber, the editor of this issue of Ideas. In the letter, the editor introduces the work of Dr. Paschalis Gkoupidenis as well as the moment in time in which his Visiting Scholars talk occurs.
Introduction To Neuromorphic Computing, Sadid R. Khan
Introduction To Neuromorphic Computing, Sadid R. Khan
Ideas: Exhibit Catalog for the Honors College Visiting Scholars Series
Neuromorphic computing is an emerging field that has the potential to drastically influence every human’s life within the next decades. Neuromorphic computing explores the computing process of the brain and attempts to replicate it onto modern electronics. It offers improvements on current computer architecture, the von Neumann architecture, and will lead to more efficient computing, easier development of machine learning, and further integration of electronics and biology.
Color Transparency From Motions Of Backgrounds And Overlays, Zhehao Huang, Qasim Zaidi
Color Transparency From Motions Of Backgrounds And Overlays, Zhehao Huang, Qasim Zaidi
MODVIS Workshop
No abstract provided.
Computations Of Top-Down Attention By Modulating V1 Dynamics, David Berga, Xavier Otazu
Computations Of Top-Down Attention By Modulating V1 Dynamics, David Berga, Xavier Otazu
MODVIS Workshop
The human visual system processes information defining what is visually conspicuous (saliency) to our perception, guiding eye movements towards certain objects depending on scene context and its feature characteristics. However, attention has been known to be biased by top-down influences (relevance), which define voluntary eye movements driven by goal-directed behavior and memory. We propose a unified model of the visual cortex able to predict, among other effects, top-down visual attention and saccadic eye movements. First, we simulate activations of early mechanisms of the visual system (RGC/LGN), by processing distinct image chromatic opponencies with Gabor-like filters. Second, we use a cortical …
Quantified Measurement Of The Tilt Effect In A Family Of Café Wall Illusions, Nasim Nematzadeh Dr., David Martin Powers Prof.
Quantified Measurement Of The Tilt Effect In A Family Of Café Wall Illusions, Nasim Nematzadeh Dr., David Martin Powers Prof.
MODVIS Workshop
This abstract explores the tilt effect in a family of Café Wall illusions using a Classical Gaussian Receptive Field model (CRF). Our model constructs an intermediate representation called edge map at multiple scales (Fig. 1) that reveals tilt cues and clues involved in the illusory perception of the Café Wall pattern. We investigate a wide range of parameters of the stimulus including mortar width, luminance, tiles contrast, and phase of the tile displacement (the stimuli in Fig. 2). We show that this simple bioplausible model, simulating the contrast sensitivity of the retinal ganglion cells, can not only detect the tilts …
An Observer Model Version Of General Recognition Theory, Fabian Soto Phd
An Observer Model Version Of General Recognition Theory, Fabian Soto Phd
MODVIS Workshop
No abstract provided.
(Poster) Design And Fabrication Of A Custom Wrist Orthosis For Enhanced Patient Comfort, Marko Tasic, Matthew Hansen, Mang Lian, Demetre Mitchell, Rashedul Sarker, Renny Fernandez, Erin Peterson, Joseph Herzog, David Olawale, Najmus Saqib
(Poster) Design And Fabrication Of A Custom Wrist Orthosis For Enhanced Patient Comfort, Marko Tasic, Matthew Hansen, Mang Lian, Demetre Mitchell, Rashedul Sarker, Renny Fernandez, Erin Peterson, Joseph Herzog, David Olawale, Najmus Saqib
ASEE IL-IN Section Conference
This custom wrist orthosis project is the continuation of efforts made by students in the R.B Annis School of Engineering during the 2017-2018 academic year. Throughout this project, we have implemented the Design for Six Sigma (DFSS) methodology to guide the design process. Within the R.B. Annis School of Engineering, this methodology has been adapted into guide the DesignSpine process. We have designed a new orthosis that is custom fabricated for enhanced patient comfort. In the occupational therapy field, patients have reportedly not been wearing their prescribed orthoses/braces, which are designed to stabilize injured areas so that they heal properly. …
Increasing Stem Literacy Through Directed Outreach, Liesl Krause, Nicole Vike, Yukai Zou, Jana Vincent
Increasing Stem Literacy Through Directed Outreach, Liesl Krause, Nicole Vike, Yukai Zou, Jana Vincent
Engagement & Service-Learning Summit
5th Annual Engagement and Service-Learning Summit: Connecting Through Listening and Scholarship, Thursday February 28th, 2019, Hosted by the Office of Engagement and Purdue Honors College
Thin Film Cocaine Sensors, Datta Sheregar, Vick Hung, Jenna Walker, Orlando Hoilett, Jacqueline Linnes, Robert Nawrocki
Thin Film Cocaine Sensors, Datta Sheregar, Vick Hung, Jenna Walker, Orlando Hoilett, Jacqueline Linnes, Robert Nawrocki
The Summer Undergraduate Research Fellowship (SURF) Symposium
Over 7 million Americans suffer from a drug use disorder and up to 60% of individuals treated for addiction will ultimately relapse. We are developing ultra-thin film electrodes on a wearable substrate for a sensor that can detect minute amounts of cocaine in sweat droplets secreted from the skin. This will enable wearable drug monitoring for personalized rehabilitation treatment plans and improve long-term addiction recovery rates. The current research focuses on developing a thin-film sensor that can be applied directly to the skin. First a layer of PVP (poly4-vinylphenol) was prepared and then spun coated onto a piece of glass. …
High-Throughput Nanoliter Dispensing Device For Biological Applications, Cole Reynolds, Euiwon Bae Dr., J Paul Robinson Dr.
High-Throughput Nanoliter Dispensing Device For Biological Applications, Cole Reynolds, Euiwon Bae Dr., J Paul Robinson Dr.
The Summer Undergraduate Research Fellowship (SURF) Symposium
Pathogen identification is a field that can contribute largely to the prevention of the spreading of illness and disease. In the past, pathogen identification has been a long and arduous process due to the time-consuming processes and steps that requires technician’s time and effort. With new technologies emerging however, screening of bacteria colonies can be done in a quick and high-throughput way. The problem is that using the current methods, bacteria cannot be transferred to petri dishes fast enough to keep up with the new screening methods. The current study focuses on exploring different methods to create an ergonomic device …
Design Modifications For A Small, Affordable Low Intensity Focused Ultrasound Device, Sui Shen, Kelsey C. Bayer, Pedro P. Irazoqui
Design Modifications For A Small, Affordable Low Intensity Focused Ultrasound Device, Sui Shen, Kelsey C. Bayer, Pedro P. Irazoqui
The Summer Undergraduate Research Fellowship (SURF) Symposium
Depression is a prevalent and serious medical illness, and while there are antidepressant drugs to mitigate depressive symptoms, 10 - 30% of patients either do not respond or develop a tolerance to these medications. Literature supports that there is an interrelation between the inflammatory response and treatment-resistant depression. A promising method to tackle depressive symptoms is to block the inflammatory signaling pathway with vagus nerve stimulation (VNS), reducing pro-inflammatory cytokine levels. Although electrical VNS devices exist, they are invasive, expensive, and have side effects including voice alteration, dyspnea, and cough. Low intensity focused ultrasound (LIFU) is a promising method that …
Rapid Sample Processing Of Foodborne Pathogens Using Cross-Flow Microfiltration, Casey Bomrad, Michael R. Ladisch, Linda Liu, Jessica Lynn Zuponcic, Eduardo Ximenes
Rapid Sample Processing Of Foodborne Pathogens Using Cross-Flow Microfiltration, Casey Bomrad, Michael R. Ladisch, Linda Liu, Jessica Lynn Zuponcic, Eduardo Ximenes
The Summer Undergraduate Research Fellowship (SURF) Symposium
Foodborne illnesses are a prominent issue, causing 48 million illnesses annually. The Escherichia coli O157:H7 outbreak in romaine lettuce is a recent example. The source of the pathogen was contaminated irrigation water. The most common methods for detecting foodborne pathogens involve cultivation and enrichment of food samples. The enrichment steps are time-consuming, taking 24 to 72 hours to complete. Our study aims to accelerate irrigation water sample preparation for pathogenic microorganism fast detection through cross-flow microfiltration. This is accomplished by a device called a continuous cell concentration and recovery device (C3D). The C3D uses cross-flow microfiltration in a hollow fiber …
Non-Invasive Diagnostic Measures Of Sensorineural Hearing Loss In Chinchillas, Hannah M. Ginsberg, Satyabrata Parida, Michael G. Heinz
Non-Invasive Diagnostic Measures Of Sensorineural Hearing Loss In Chinchillas, Hannah M. Ginsberg, Satyabrata Parida, Michael G. Heinz
The Summer Undergraduate Research Fellowship (SURF) Symposium
According to the World Health Organization, disabling hearing loss affects nearly 466 million people worldwide. Sensorineural hearing loss (SNHL), which is characterized as damage to the inner ear (e.g., cochlear hair cells) and/or to the neural pathways connecting the inner ear and brain, accounts for 90% of all disabling hearing loss. More concerning is that significant perceptual and physiological aspects of SNHL remain “hidden” from standard clinical diagnostics. Hidden hearing loss (HHL) manifests as the inability to understand speech in loud, noisy environments (e.g., listening in a noisy restaurant) despite a normal audiogram (i.e., normal detection of soft sounds). Recently, …
Flow Chamber For Confocal Tracking Of Particles In Bone, Brennan Flannery, Russell Main, Xiaoyu Xu
Flow Chamber For Confocal Tracking Of Particles In Bone, Brennan Flannery, Russell Main, Xiaoyu Xu
The Summer Undergraduate Research Fellowship (SURF) Symposium
Interstitial fluid flow in the lacunar-canalicular system (LCS) of bone is recognized as a potential regulator of bone remodeling. Movement of fluid across bone cells called osteocytes regulates gene expression that leads to either bone formation or resorption. Interstitial fluid moves in response to bone loading during daily activity, and bone growth occurs to compensate for these loads, affecting bone shape and strength. While interstitial fluid flow is thoroughly studied using computational models, there is a critical need to study flow in real bone samples with imaging techniques. Flow velocities determined from imaging will be more accurate than computational models …
Bacteria Movement Near Surfaces, Shulin Wang, Adib Ahmadzadegan, Arezoo Ardekani
Bacteria Movement Near Surfaces, Shulin Wang, Adib Ahmadzadegan, Arezoo Ardekani
The Summer Undergraduate Research Fellowship (SURF) Symposium
Understanding the behaviors of bacteria near surfaces is crucial in many biological and ecological applications. This knowledge can be used to hinder undesired biofilm formation on medical instruments and wounds. On top of that, it could also provide further insights in biodegradation of dispersed oil. In this work, the behavior of Escherichia Coli near a surface was experimentally studied. We utilized an inverted microscope in the phase filed illumination mode and processed acquired images to track the motions of bacteria near surfaces with high accuracy and repeatability. Distribution of the cells when they reached a steady state shows that the …
Improving Biomanufacturing Production With Novel Elp-Based Transcriptional Regulators, Juya Jeon, Logan R. Readnour, Kevin V. Solomon
Improving Biomanufacturing Production With Novel Elp-Based Transcriptional Regulators, Juya Jeon, Logan R. Readnour, Kevin V. Solomon
The Summer Undergraduate Research Fellowship (SURF) Symposium
Microbes can be used to produce valuable drugs, chemicals, and biofuels, but their potential has not been fully realized due to low production yields. To improve biomanufacturing processes and yield, we are developing novel, transcriptional regulators using biosynthesis technology in order to improve cellular health and overall production. Our regulator contains elastin-like polypeptides (ELPs), which make ideal sensors since they exhibit a sharp, inverse phase transition to indicators of cell health such as intracellular pH and ionic strength, and external stimuli such as temperature. We hypothesize that ELP can be fused to transcription factors to control expression of target genes. …
Characterization And Quantification Of Fibrin Gel Mechanics With Fibroblast Invasion, Nicklaus Iavagnilio, Sarah Calve, Adrian Buganza-Tepole
Characterization And Quantification Of Fibrin Gel Mechanics With Fibroblast Invasion, Nicklaus Iavagnilio, Sarah Calve, Adrian Buganza-Tepole
The Summer Undergraduate Research Fellowship (SURF) Symposium
Cutaneous wounds undergo an intricate healing process stimulated by a variety of local mechanical and biological stimuli that lead to patterns of growth and remodeling. Despite significant research in dermal wound healing, pathological scarring is still common particularly in wounds closed under mechanical stress, or large wounds left to heal by secondary intention. The purpose of this study is to utilize previously established wound healing models using fibrin gels and fibroblasts to better understand the functional relationships of the biological processes of normal compared to abnormal wound healing. Increases in uni-axial strain and transforming growth factor beta-1 concentration have been …
Cost-Effective Paper-Based Diagnostic Using Split Proteins To Detect Yeast Infections, Zachary R. Berglund, Kevin V. Solomon, Mohit S. Verma, Moiz Rasheed, Zachary Hartley, Kevin Fitzgerald, Kok Zhi Lee, Janice Chan, Julianne Dejoie, Makayla Schacht, Alex Zavala
Cost-Effective Paper-Based Diagnostic Using Split Proteins To Detect Yeast Infections, Zachary R. Berglund, Kevin V. Solomon, Mohit S. Verma, Moiz Rasheed, Zachary Hartley, Kevin Fitzgerald, Kok Zhi Lee, Janice Chan, Julianne Dejoie, Makayla Schacht, Alex Zavala
The Summer Undergraduate Research Fellowship (SURF) Symposium
The common yeast infection, vulvovaginal candidiasis, affects three out of four women throughout their lifetime and can be spread to their child in the form of oral candidiasis (thrush). This disease is caused by the fungal pathogen Candida albicans, which is also a major cause of systemic candidiasis, a rarer but deadly disease with up to a 49% lethality rate. Current widely-used diagnostic methods include cell cultures, pH tests, and antibody detection, to assist effective treatment. Despite availability of various diagnostic methods, there is no inexpensive, rapid, and accurate way to detect C. albicans infection. This project aims to …
Magnetically Actuated Cell Stretching Platform To Induce Phenotypic Changes In Metastatic Cells, Yong Gyun Cho, Hyunsu Park, Hyowon Lee, Sarah Libring
Magnetically Actuated Cell Stretching Platform To Induce Phenotypic Changes In Metastatic Cells, Yong Gyun Cho, Hyunsu Park, Hyowon Lee, Sarah Libring
The Summer Undergraduate Research Fellowship (SURF) Symposium
Although metastasis is responsible for about 90% of cancer deaths, only few in vitro models can be used to evaluate dynamic behaviors of metastatic cancer cells. Many studies have shown that mechanical stimuli can trigger various cellular responses such as gene and protein expression, which could lead to changes in cellular phenotype. Similarly, metastasized breast cancer cells in the lung tissue are constantly stretched by cyclic mechanical stress due to breathing, which alters cellular morphology and proliferation state. Such transitions can make the secondary tumors resistant to the chemotherapy used to effectively treat the primary tumors. In this work, we …
Developing Strategies To Toughen Bio-Inspired Adhesives, Narelli P. Narciso, Samuel Lee Huntington, Jonathan J. Wilker
Developing Strategies To Toughen Bio-Inspired Adhesives, Narelli P. Narciso, Samuel Lee Huntington, Jonathan J. Wilker
The Summer Undergraduate Research Fellowship (SURF) Symposium
Mussels and other marine creatures adhere very well in underwater environments, having the ability to withstand the force of the sea. These animals have inspired synthetic biomimetic adhesives for wet systems, presenting potential for biomedical applications. However, most current commercial adhesives tend to be brittle, not resisting repetitive movements. This study assesses toughening strategies to improve the mussel-inspired adhesives’ ductility while maintaining its strength. The strategies included altering the polymer’s chemical structure by changing the percentage of polyethylene glycol (PEG) in the molecule and by adding fillers, such as calcium carbonate, silica and nacre - a calcium carbonate compound found …
Tissue Clearing As A Mechanism To Identify Changes In Fibronectin Structure During Breast Cancer Metastasis, Maryam Nuru, Kelsey Hopkins, Luis Solorio
Tissue Clearing As A Mechanism To Identify Changes In Fibronectin Structure During Breast Cancer Metastasis, Maryam Nuru, Kelsey Hopkins, Luis Solorio
The Summer Undergraduate Research Fellowship (SURF) Symposium
With metastasis accounting for approximately 90% of breast cancer deaths and an alarming number of over 300,000 new breast cancer cases to be diagnosed by the end of 2018, there is growing need to understand the process of breast cancer. Changes in the extracellular matrix (ECM) of the tumor microenvironment play an essential role in this deadly tumor progression. Specifically, the glycoprotein fibronectin (FN), has been identified to be up-regulated in patients with worse clinical outcomes. During tumor progression fibronectin undergoes conformational changes that aid in metastatic dissemination. In order to analyze the dynamic changes in FN expression and evaluate …
Creating A Mammary Duct Model To Study The Effects Of Cancer Heterogeneity On Tumor Metastasis, Megan Hofstetter, Mazin Hakim, Luis Solorio
Creating A Mammary Duct Model To Study The Effects Of Cancer Heterogeneity On Tumor Metastasis, Megan Hofstetter, Mazin Hakim, Luis Solorio
The Summer Undergraduate Research Fellowship (SURF) Symposium
During tumor progression, the process of clonal evolution gives rise to a variety of cell subpopulations that cause differential sensitivity to drugs and give rise to cell populations with the ability to metastasize, there are many mouse models available that can be used to study tumor progression and metastasis. However, there is a lack of models to study the effect of tumor heterogeneity using human cancers. Xenograft based systems require the use of immunodeficient mice, which limits the use of the model to evaluate microenvironmental factors involved in metastatic dissemination. Humanized mouse models with established human immune systems have been …
Method Validation Of Functional Magnetic Resonance Imaging And Electrophysiological Recording To Investigate Mechanisms Of Vagus Nerve, Christina L. Hendren, Jiayue Cao, Zhongming Liu
Method Validation Of Functional Magnetic Resonance Imaging And Electrophysiological Recording To Investigate Mechanisms Of Vagus Nerve, Christina L. Hendren, Jiayue Cao, Zhongming Liu
The Summer Undergraduate Research Fellowship (SURF) Symposium
Vagus nerve stimulation (VNS) is used clinically to treat epilepsy and depression, but its mechanism of action is unknown. Useful techniques to study this are functional magnetic resonance imaging (fMRI) and the local field potential (LFP). fMRI relies on oxygen use in the brain to show areas where neurons are active. The LFP is an electrical signal created by neuron action potentials and other current moving across cell membranes. The most information can be gained when the two methods are used simultaneously, however, this is difficult to do. This study seeks to validate the technique of fMRI-LFP as applied to …
Fluidic Control With Wax Valves For Paper-Based Diagnostics, Emilie I. Newsham, Elizabeth A. Phillips, Katherine N. Clayton, Jacqueline C. Linnes
Fluidic Control With Wax Valves For Paper-Based Diagnostics, Emilie I. Newsham, Elizabeth A. Phillips, Katherine N. Clayton, Jacqueline C. Linnes
The Summer Undergraduate Research Fellowship (SURF) Symposium
Paper-fluidic devices are a common platform for point-of-care disease detection in under-resourced areas because of their low cost and minimal instrumentation requirements. Limited fluidic control in paper-fluidic devices has hindered the incorporation of multistep reactions that are necessary for more sensitive disease detection. One potential fluidic control mechanism is the incorporation of thermally actuated wax valves to separate assay stages. Such valving would expand the detection capabilities of these devices by permitting fluid obstruction for sustained reactions and facilitating controlled volume release within a fully-automated, self-contained device. Despite the potential to exploit wax valves for innovative paper-fluidic diagnostics, a thorough, …
Neural Coding Of An Auditory Pitch Illusion, Maria Alejandra Barrera, Mark Sayles, Ravinderjit Singh
Neural Coding Of An Auditory Pitch Illusion, Maria Alejandra Barrera, Mark Sayles, Ravinderjit Singh
The Summer Undergraduate Research Fellowship (SURF) Symposium
Pitch is an important perceptual dimension in audition, supporting auditory object segregation, melody recognition and lexical distinction. Huggins’ pitch, for example, is a phenomenon evoked by two sources of broadband noise presented binaurally with an inter-aural phase shift over a narrow frequency band. Huggins’ pitch and other dichotic pitches have been studied extensively using perceptual experiments. Several models have been proposed to explain and predict the perception of pitch; however, no studies have tried to record in vivo neuron responses to Huggins’ pitch (HP) nor have tried to explain how the HP is coded by neurons. The existence of pitches …