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Biomechanics Of Retinal Venous Pulsations As Indicators Of Intracranial Pressure, Charles F. Babbs
Biomechanics Of Retinal Venous Pulsations As Indicators Of Intracranial Pressure, Charles F. Babbs
Weldon School of Biomedical Engineering Faculty Working Papers
The origin of retinal venous pulsations remains an open problem in physiology and medicine; so too, their exact relationship to intracranial pressure. This study takes a mathematical modeling approach to explore details of blood flow through the eye to reveal the mechanism of pulsations. The intravaginal, intraneural, and intraocular segments of the retinal arteries and veins are modeled as connected resistive-capacitive segments. The analysis incorporates two critical mechanical properties of these small blood vessels, not heretofore studied, which become significant under conditions of negative transmural pressures: (1) dramatically reduced compliance during flattening and (2) cross-sectional shape change as internal volume …