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Full-Text Articles in Biomedical Engineering and Bioengineering
Characterization And Limitations Of Diffusion Tensor Imaging Metrics In The Cervical Spinal Cord In Neurologically Intact Subjects, Aditya Vedantam, Michael B. Jirjis, Brian D. Schmit, Marjorie C. Wang, John L. Ulmer, Shekar N. Kurpad
Characterization And Limitations Of Diffusion Tensor Imaging Metrics In The Cervical Spinal Cord In Neurologically Intact Subjects, Aditya Vedantam, Michael B. Jirjis, Brian D. Schmit, Marjorie C. Wang, John L. Ulmer, Shekar N. Kurpad
Biomedical Engineering Faculty Research and Publications
Purpose
To characterize diffusion tensor imaging (DTI) metrics across all levels of the cervical spinal cord (CSC) and to study the impact of age and signal quality on these metrics.
Materials and Methods
DTI metrics were calculated for gray matter (GM) and white matter (WM) funiculi throughout the CSC (C1–T1) in 25 healthy subjects (22-85 years old). Signal-to-noise ratios (SNRs) and mean DTI metrics were measured for the upper (C1-3), middle (C4-6) and lower (C7-T1) cervical segments. Age-related changes in DTI metrics were analyzed for the individual segment groups.
Results
Fractional anisotropy (FA), mean diffusivity (MD) and transverse apparent diffusion …