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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Blow-Spun Hybrid Pcl-Peo/Hnts Scaffolds With Enhanced Biological And Mechanical Properties, Meichen Liu
Blow-Spun Hybrid Pcl-Peo/Hnts Scaffolds With Enhanced Biological And Mechanical Properties, Meichen Liu
Doctoral Dissertations
With the development of technology and engineering, nanotechnology has been a multidisciplinary scientific field applied in nearly all science areas, including medicine, genetics, food industry, robotics. In this respect, nanomedicine has gained increasing attention and been a useful, effective therapy for cancer diagnosis, gene transfer, and drug delivery. To design an ideal nano drug delivery system with controlled drug releasing and improved encapsulated drug’s pharmacokinetic and pharmacodynamic profiles, hydrogels and polymer composites have witnessed increased research interest during the last decades. Recently, numerous polymers have been studied to fabricate the ideal wound dressing with biocompatibility, biodegradability, porous structural, and suitable …
Application Of Halloysite Nanotubes In Bone Disease Remediation And Bone Regeneration, Yangyang Luo
Application Of Halloysite Nanotubes In Bone Disease Remediation And Bone Regeneration, Yangyang Luo
Doctoral Dissertations
Customized patient therapy has been a major research focus in recent years. There are two research fields that have made a significant contribution to realizing individualized-based treatment: targeted drug delivery and three-dimensional (3D) printing technology. With benefit from the advances in nanotechnology and biomaterial science, various drug delivery systems have been established to provide precise control of therapeutic agents release in time and space. The emergence of three-dimensional (3D) printing technology enables the fabrication of complicated structures that effectively mimic native tissues and makes it possible to print patient-specific implants. My dissertation research used a clay nanoparticle, halloysite, to develop …
Two And Three-Dimensional Models For Material And Cells Interaction, Nam H. Nguyen
Two And Three-Dimensional Models For Material And Cells Interaction, Nam H. Nguyen
Doctoral Dissertations
Three-dimensional (3D) cell spheroid model has been long considered a better model to mimic in vivo physiology compared to two-dimensional (2D) cell culture model. Traditional 2D cell models provide a simple, convenient and quick technique for drug screening but fail to simulate the complexity and heterogeneity of cells in the in vivo environment. The last few decades have remarked substantial progress toward the advancement of three-dimensional (3D) cell cultures as systems which better mimic cellcell and cell-matrix interaction in the in vivo physiology. Nowadays, 3D cell models have been emerging, not only as an important approach in drug discovery and …
Integration Of Micro Nano And Bio Technologies With Layer -By -Layer Self -Assembly, Dinesh Shankar Kommireddy
Integration Of Micro Nano And Bio Technologies With Layer -By -Layer Self -Assembly, Dinesh Shankar Kommireddy
Doctoral Dissertations
In the past decade, layer-by-layer (LbL) nanoassembly has been used as a tool for immobilization and surface modification of materials with applications in biology and physical sciences. Often, in such applications, LbL assembly is integrated with various techniques to form functional surface coatings and immobilized matrices. In this work, integration of LbL with microfabrication and microfluidics, and tissue engineering are explored. In an effort to integrate microfabrication with LbL nanoassembly, microchannels were fabricated using soft-lithography and the surface of these channels was used for the immobilization of materials using LbL and laminar flow patterning. Synthesis of poly(dimethyldiallyl ammonium chloride)/poly(styrene sulfonate) …