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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Detection Of Antibodies Directed At M. Hyorhinis P37 In The Serum Of Men With Newly Diagnosed Prostate Cancer, Cydney Urbanek, Steve Goodison, Myron Chang, Stacy Porvasnik, Noburo Sakamoto, Chen-Zhong Li, Susan K. Boehlein, Charles J. Rosser Jun 2011

Detection Of Antibodies Directed At M. Hyorhinis P37 In The Serum Of Men With Newly Diagnosed Prostate Cancer, Cydney Urbanek, Steve Goodison, Myron Chang, Stacy Porvasnik, Noburo Sakamoto, Chen-Zhong Li, Susan K. Boehlein, Charles J. Rosser

Department of Biomedical Engineering Faculty Publications

Background: Recent epidemiologic, genetic, and molecular studies suggest infection and inflammation initiate certain cancers, including cancers of the prostate. Over the past several years, our group has been studying how mycoplasmas could possibly initiate and propagate cancers of the prostate. Specifically, Mycoplasma hyorhinis encoded protein p37 was found to promote invasion of prostate cancer cells and cause changes in growth, morphology and gene expression of these cells to a more aggressive phenotype. Moreover, we found that chronic exposure of benign human prostate cells to M. hyorhinis resulted in significant phenotypic and karyotypic changes that ultimately resulted in the malignant transformation …


Bme Annual Report 2010-2011, Department Of Biomedical Engineering, Florida International University Jun 2011

Bme Annual Report 2010-2011, Department Of Biomedical Engineering, Florida International University

Biomedical Engineering Department Annual Reports

No abstract provided.


Spectral-Profile-Based Algorithm For Hemoglobin Oxygen Saturation Determination From Diffuse Reflectance Spectra, Po-Ching Chen, Wei-Chiang Lin Apr 2011

Spectral-Profile-Based Algorithm For Hemoglobin Oxygen Saturation Determination From Diffuse Reflectance Spectra, Po-Ching Chen, Wei-Chiang Lin

Department of Biomedical Engineering Faculty Publications

Variations of hemoglobin (Hb) oxygenation in tissue provide important indications concerning the physiological conditions of tissue, and the data related to these variations are of intense interest in medical research as well as in clinical care. In this study, we derived a new algorithm to estimate Hb oxygenation from diffuse reflectance spectra. The algorithm was developed based on the unique spectral profile differences between the extinction coefficient spectra of oxy-Hb and deoxy-Hb within the visible wavelength region. Using differential wavelet transformation, these differences were quantified using the locations of certain spectral features, and, then, they were related to the oxygenation …