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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Effect Of Blood Flow Patterns On Localized Platelet Adhesion Under Physiologic Flow Conditions Using Two-Dimensional And Three-Dimensional Stent Models - An Experimental And Computational Approach, Nandini Duraiswamy
FIU Electronic Theses and Dissertations
This dissertation presents dynamic flow experiments with fluorescently labeled platelets to allow for spatial observation of wall attachrent in inter-strut spacings, to investigate their relationship to flow patterns. Human blood with fluorescently labeled platelets was circulated through an in vitro system that produced physiologic pulsatile flow in (1) a parallel plate flow chamber that contained two-dimensional (2D) stents that feature completely recirculating flow, partially recirculating flow, and completely reattached flow, and (2) a three-dimensional (3D) cylindrical tube that contained stents of various geometric designs.
Flow detachment and reattachment points exhibited very low platelet deposition. Platelet deposition was very low in …
Bme Annual Report 2004-2005, Department Of Biomedical Engineering, Florida International University
Bme Annual Report 2004-2005, Department Of Biomedical Engineering, Florida International University
Biomedical Engineering Department Annual Reports
No abstract provided.
Characterization Of Cerebral Blood Flow Response To Traumatic Brain Injury In An Animal Model Using Spect., Michael Capille
Characterization Of Cerebral Blood Flow Response To Traumatic Brain Injury In An Animal Model Using Spect., Michael Capille
FIU Electronic Theses and Dissertations
In this study the focal effects of moderate traumatic brain injury (TBI) on cerebral blood flow (CBF) as reported by SPECT cerebral brain perfusion (CBP) imaging in an animal model were investigated by parallelized statistical techniques. Subjects were randomly assigned to either a control group or test group receiving fluid percussion injury directly to the left parietal lobe.
Qualitative SPECT CBP accuracy was assessed against reference radioactive microsphere technique (RMT) regional CBF measurements by map reconstruction, registration and smoothing. Cerebral hypoperfusion in the test group was then identified at the voxel level using a statistical parametric mapping (SPM) model.
Using …