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Full-Text Articles in Biomedical Engineering and Bioengineering
Novel In-Vitro Epilepsy Ipsc Model, Anthony Giordano
Novel In-Vitro Epilepsy Ipsc Model, Anthony Giordano
Undergraduate Research at FIU (URFIU) Conference
The main focus of this ARCH research project is to create a novel in-vitro epilepsy model will using iPSC techniques. Neural tissue will be collected from both epileptic and control rats and then the neural tissue will be induced to pluripotent stem cells and regrown in a petri dish. It has been hypothesized that the regrown stem cells will have the same genetic characteristics as the host cells they come from. To confirm this both Western Blot and RTPCR will be performed on both the host tissue and the newly grown astrocytes and neurons (of both epileptic and control rats) …
Mass Spectrometric Lipidomic Analyses Of Human Aqueous Humor, Catalina Garzon
Mass Spectrometric Lipidomic Analyses Of Human Aqueous Humor, Catalina Garzon
Undergraduate Research at FIU (URFIU) Conference
Primary Open Angle Glaucoma, the leading cause for peripheral blindness in the United States, has an etiology not completely understood but highly related to elevated levels of intraocular pressure. Presumably, the plasma membrane, mainly composed of phospholipids, of the cells experience imperative structural and functional changes during the glaucoma neuropathy. Previous studies were unable to adequately investigate ocular lipidomics because of low lipid yield and sub-par identification and quantification methods until the recent advent of mass spectrometry. The objective of the project is to understand how to use mass spectrometry to characterize 4 classes of phospholipids in terms of quantity …
Systematic Monitoring Of Wound Healing Using A Hand-Held Near-Infrared Optical Scanner, Stephanie Gonzalez, Elizabeth Solis, Suset Rodriguez
Systematic Monitoring Of Wound Healing Using A Hand-Held Near-Infrared Optical Scanner, Stephanie Gonzalez, Elizabeth Solis, Suset Rodriguez
Undergraduate Research at FIU (URFIU) Conference
According to the American Podiatric Medical Association, about 15 percent of the patients with diabetes would develop a diabetic foot ulcer. Furthermore, foot ulcerations leads to 85 percent of the diabetes-related amputations. Foot ulcers are caused due to a combination of factors, such as lack of feeling in the foot, poor circulation, foot deformities and the duration of the diabetes. To date, the wounds are inspected visually to monitor the wound healing, without any objective imaging approach to look before the wound’s surface. Herein, a non-contact, portable handheld optical device was developed at the Optical Imaging Laboratory as an objective …