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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Shape Memory Alloy Capsule Micropump For Drug Delivery Applications, Youssef Mohamed Kotb Jun 2024

Shape Memory Alloy Capsule Micropump For Drug Delivery Applications, Youssef Mohamed Kotb

Theses and Dissertations

Implantable drug delivery devices have many benefits over traditional drug administration techniques and have attracted a lot of attention in recent years. By delivering the medication directly to the tissue, they enable the use of larger localized concentrations, enhancing the efficacy of the treatment. Passive-release drug delivery systems, one of the various ways to provide medication, are great inventions. However, they cannot dispense the medication on demand since they are nonprogrammable. Therefore, active actuators are more advantageous in delivery applications. Smart material actuators, however, have greatly increased in popularity for manufacturing wearable and implantable micropumps due to their high energy …


Borophene And Graphene For Non-Enzymatic Biosensor- Ab-Initio Study, Omar A. Ismail Dec 2023

Borophene And Graphene For Non-Enzymatic Biosensor- Ab-Initio Study, Omar A. Ismail

Theses and Dissertations

Non-enzymatic glucose sensing holds promise to overcome limitations associated with glucose oxidase, such as oxygen dependence and short shelf life. This study explores the potential sensing capabilities of borophene and graphene through direct interaction with various compounds, including β-glucose, uric acid, ascorbic acid, fructose, and acetaminophen. Using Density Functional Theory (DFT), we calculated binding energies and the respective Density of States (DOS) for these adsorbates on both graphene and borophene surfaces. Preliminary results suggest that borophene might exhibit nearly twice the affinity for β-glucose compared to graphene. Moreover, the calculated Density of States reveals distinct distortions in the electronic states …


An Epileptic Seizure Detection Method From Eeg Signals Based On A Classifier-Driven Feature Reduction Technique, Raymond N. Kamel Jan 2023

An Epileptic Seizure Detection Method From Eeg Signals Based On A Classifier-Driven Feature Reduction Technique, Raymond N. Kamel

Theses and Dissertations

Epileptic seizure detection can improve the quality of life of epileptic patients, allow for more accurate medication, and minimize the risk of sudden unexpected death in epilepsy (SUDEP). This thesis work aims to develop a robust and stable algorithm for epileptic seizure detection through the classification of EEG signals. To achieve this aim, a methodology is proposed to develop a classifier that can differentiate between the healthy (normal), interictal, and ictal states of EEG signals, while maximizing the classification accuracy and minimizing the computational redundancy. The main pillar upon which this methodology is designed is using a problem-specific classifier-driven feature …