Biomedical Engineering and Bioengineering Commons^™

A Continuous Process For The Conversion Of Vegetable Oils Into Methyl Esters Of Fatty Acids, Hossein Noureddini, D Harkey, V Medikonduru

Papers in Biomaterials

A continuous process for the transesterification of triglycerides to methyl esters was investigated in a pilot plant. The process was equipped with a motionless and a high-shear mixer. The experimental studies explored variations in the mixing intensity, stoichiometry, and catalyst concentration on the overall conversion. The combined as well as individual effect of mixers was examined. The developed process resulted in high conversions of vegetable oils into methyl esters. Conversion of triglycerides to methyl esters in excess of 98% was achieved. Larger excess amounts of alcohol favored higher conversions. The motionless and high-shear mixers each provided adequate mixing for the …

Enzymatic Glycerolysis Of Soybean Oil , Hossein Noureddini, S E. Harmeier

Papers in Biomaterials

Enzymatic glycerolysis of soybean oil was studied. Of the nine lipases that were tested in the initial screening, Pseudomonas sp. resulted in the highest yield of monoglycerides. Lipase from Pseudomonas sp. was further studied for the influence of temperature, thermal stability, enzyme/oil ratio, and glycerol/oil ratio. A full factorial optimization approach was performed. The following conditions were tested over the specified ranges: temperature (30?70°C), thermal stability (30?70°C), enzyme/oil ratio (0.05?0.2 g enzyme/10 g oil), glycerol/oil ratio (1:1?3:1 glycerol/oil molar ratio) and 1 h reaction time. The stability of the enzyme at the reaction temperature was also incorporated as a separate …

Method For Improving Consolidation Of Powder Resin, David A. Pienkowski, Eric A. Grulke, Robert J. Jacob

Biomedical Engineering Faculty Patents

A method for improving consolidation of powder resin is provided. The method broadly includes the steps of: (1) sorting particles of the powder resin according to their diameter; (2) combining the sorted particles having a first diameter D1 with the sorted particles having a second diameter D2 so as to form a particle mixture; (3) applying a vibration to the particle mixture; (4) heating the particle mixture; and (5) delivering the particle mixture through a nozzle or into a mold. The particle diameters D1 and D2 are chosen so that once combined there is optimal close packing of the three-dimensional …

Runoff And Erosion Following Field Application Of Beef Cattle Manure And Compost, John E. Gilley, Bahman Eghball

Biological Systems Engineering: Papers and Publications

Manure or compost from beef cattle feedlots can be excellent sources of nutrients and organic matter when added to soils. This study was conducted to determine the effect of a single application of manure and compost on runoff and erosion under no-till and tillage conditions. Tillage consisted of a single disking operation up and down the slope on a Sharpsburg soil which was cropped to grain sorghum or wheat the previous season. Manure and compost were applied at rates required to meet corn fertility requirements. Additional experimental treatments included the application of inorganic fertilizer and an untreated check. The addition …

Quantification Of Mitral Regurgitation With Mr Phase-Velocity Mapping Using A Control Volume Method, George P. Chatzimavroudis, John N. Oshinski, Roderic I. Pettigrew, Peter G. Walker, Robert H. Franch, Ajit P. Yoganathan

Chemical & Biomedical Engineering Faculty Publications

Reliable diagnosis and quantification of mitral regurgitation are important for patient management and for optimizing the time for surgery. Previous methods have often provided suboptimal results. The aim of this in vitro study was to evaluate MR phase-velocity mapping in quantifying the mitral regurgitant volume (MRV) using a control volume (CV) method. A number of contiguous slices were acquired with all three velocity components measured. A CV was then selected, encompassing the regurgitant orifice. Mass conservation dictates that the net inflow into the CV should be equal to the regurgitant flow. Results showed that a CV, the boundary voxels of …

Multidirectional Ecg Coherent Optimal Timing Of Defibrillation Shocks, Abhijit R. Patwardhan, Fabio M. Leonelli

Biomedical Engineering Faculty Patents

A method for of delivering a defibrillation shock to a heart at an optimal time to stop ventricular fibrillation which involves obtaining an electrocardiogram of a heart in at least two directions, determining a time-coherency of the electrocardiogram based upon each of the at least two directions, and computing a tracking function from the time-coherency. An optimal time to apply a defibrillation shock to the heart is determined by locating a local maximum on the tracking function. The method utilizes spacia characteristics of the ventricular fibrillation. The method can be incorporated into implantable cardioverter defibrillators utilizing existing hardware technology.

Method For Reducing The Generation Of Wear Particulates From An Implant, David A. Pienkowski, Kwon-Yong Lee

Biomedical Engineering Faculty Patents

A method is provided for reducing the amount of wear particulates generated by a total joint orthopaedic implant. The implant consists of two matched articulating components wherein at least one of the components is made of polymer or other material with similar physical properties. The method includes the steps of placing the total joint orthopaedic implant in a fluid bath and articulating the implant in the fluid bath for at least 1,000 cycles. The articulation may be performed in three stages. In the first, the implant is articulated under a load of substantially 0.1-500 Newtons with sliding speeds of substantially …

Biodiesel Fuel From Animal Fat. Ancillary Studies On Transesterification Of Beef Tallow, Fangrui Ma, L. Davis Clements, Milford Hanna

Nebraska Center for Biotechnology: Faculty and Staff Publications

Transesterification of beef tallow was investigated. The solubility of ethanol in beef tallow was much higher than that of methanol. At 100 °C the solubility of methanol was 19% (w/w). The solubility of ethanol in beef tallow reached 100% (w/w) at about 68 °C. For the distribution of methanol between beef tallow methyl esters (BTME) and glycerol, the percentage of total methanol in the glycerol phase was higher than that in the fatty acid methyl ester (FAME) phase in a simulated system at room temperature. At 65-80 °C, however, the percentage of total methanol in FAME (60% (w/w)) was higher …

Current Concepts Review - Corrosion Of Metal Orthopaedic Implants, Joshua J. Jacobs, Jeremy L. Gilbert, Robert M. Urban

Biomedical and Chemical Engineering - All Scholarship

No abstract provided.

Multiresolution Detection Of Spiculated Lesions In Digital Mammograms, Sheng Liu, Charles F. Babbs, Edward Delp

Weldon School of Biomedical Engineering Faculty Publications

In this paper we present a novel multiresolution scheme for the detection of spiculated lesions in digital mammograms. First, a multiresolution representation of the original mammogram is obtained using a linear phase nonseparable 2-D wavelet transform. A set of features is then extracted at each resolution in the wavelet pyramid for every pixel. This approach addresses the difficulty of predetermining the neighborhood size for feature extraction to characterize objects that may appear in different sizes. Detection is performed from the coarsest resolution to the finest resolution using a binary tree classifier. This top-down approach requires less computation by starting with …

Controlled Environment Potentiostat To Study Solid-Aqueous Systems, R A. Petrie, P. R. Grossl, Ronald C. Sims

Biological Engineering Faculty Publications

We designed a redox apparatus that controls electropotenial (Eh), pH, and temperature. The apparatus is fully automated and can be assembled from equipment found in most soil analytical laboratories. The reactor can maintain environmental conditions used to evaluate the chemical fate of contaminants under natural conditions (natural attenuation) or adjust them to a new steady state to evaluate the effect of engineered remediation on a subsurface system. It can operate within a wide range of redox potential values (−400 to 400 mV) and at any pH value. The stability and accuracy of the instrument was tested by performing Eh-pH titrations …

Production Of Ethers Of Glycerol From Crude Glycerol - The By-Product Of Biodlesel Production, Hossein Noureddini, W R. Dailey, B A. Hunt

Papers in Biomaterials

Methyl esters of fatty acids (also known as biodiesel), made from the transesterification of vegetable oils and animal fats with methanol, have shown a lot of promise as alternative diesel fuels. Glycerol is the inevitable byproduct of the trans-esterification process. While there are existing markets for glycerol, a significant increase in availability of glycerol, re-sulting from the expanded use of vegetable oils and animal fats, would destabilize the glycerol market. Direct addition of glycerol to the fuel is not possible, however, derivatives of glycerol such as ethers have potential for use as additives with biodiesel, diesel or biodiesel-diesel blends. In …

Sensory Changes In Adults With Unilateral Transtibial Amputation, Judith B. Kosasih, Barbara Silver-Thorn

Biomedical Engineering Faculty Research and Publications

The purpose of this study was to describe the sensory changes in adults with unilateral transtibial amputation

(TTA), as any loss of sensation may have significant impact on the successful use of a prosthesis. Sensory modalities of light touch, deep pressure, vibration, and superficial pain (pinprick) were examined on the residual and contralateral limbs of 16 veterans with TTA. Six subjects demonstrated normal sensation on the contralateral limb and impaired sensation of superficial pain, vibration, and/or light touch on the residual limb. Superficial pain was the most frequently impaired sensation, and vibration and superficial pain sensation appeared to be age-dependent, …

Opto-Electronic Sensor System For Rapid Evaluation Of Planter Seed Spacing Uniformity, Michael F. Kocher, Yubin Lan, Changhe Chen, John A. Smith

Biological Systems Engineering: Papers and Publications

An opto-electronic seed spacing evaluation system that measured time intervals between seeds and detected front-to-back location of seed drop events relative to the planter was used to rapidly determine planter seed spacing uniformity in the laboratory. The seed detection sensor for the opto-electronic system consisted of a rectangular photogate with 24 phototransistors receiving light beams from 24 LEDs opposite to them. The system also included circuitry to interface the photogate with a digital I/O board in a personal computer. The opto-electronic system was tested with three planter configurations. During the tests, the photogate was positioned beneath the seed drop tube …

Cryptococcus Neoformans Chemotyping By Quantitative Analysis Of H-1 Nuclear Magnetic Resonance Spectra Of Glucuronoxylomannans With A Computer-Simulated Artificial Neural Network, Robert Cherniak, Homayoun Valafar, Laura C. Morris, Faramarz Valafar

Faculty Publications

The complete assignment of the proton chemical shifts obtained by nuclear magnetic resonance (NMR) spectroscopy of de-O-acetylated glucuronoxylomannans (GXMs) from Cryptococcus neoformanspermitted the high-resolution determination of the total structure of any GXM. Six structural motifs based on an α-(1→3)-mannotriose substituted with variable quantities of 2-O-β- and 4-O-β-xylopyranosyl and 2-O-β-glucopyranosyluronic acid were identified. The chemical shifts of only the anomeric protons of the mannosyl residues served as structure reporter groups (SRG) for the identification and quantitation of the six triads present in any GXM. The assigned protons for the mannosyl residues resonated at clearly …

Relationships Among Grain Sorghum Quality Factors, Roberto A. Buffo, Curtis L. Weller, Anne M. Parkhurst

Biological Systems Engineering: Papers and Publications

Correlations among grain sorghum quality factors (proximate composition, physical properties, and water absorption properties) were evaluated. Samples of 46 commercial hybrids (24 and 22 from crop years 1993 and 1994) were analyzed for starch, protein, crude free fat, test weight, absolute density, 1,000 kernel weight, percent kernel abraded, water absorption index, initial water absorption rate, and moisture saturation point. Test weight, absolute density, and percent kernel abraded were positively correlated among themselves (r > 0.5). Protein was negatively correlated with both test weight and absolute density (r < -0.5), while moisture saturation point showed negative correlations with test weight, absolute density, 1,000 kernel weight, and percent kernel abraded (r < -0.4). Principal component factor analysis through the covariance matrix explained 95% of the total variation of quality factors among hybrids (two factors), and, through the correlation matrix, 85% of the total variation (five factors). Water absorption rate decreased with increasing starch content of grain sorghum kernels as water absorption rate increased and amount of water for saturation decreased with softening of kernels.

Design Of Tapered Augers For Uniform Unloading Particulate Material From Rectangular Cross-Section Containers, M. S. Burr, Michael F. Kocher, David D. Jones

Biological Systems Engineering: Papers and Publications

The design equation for an auger to provide uniform unloading of particulate material from a container with a rectangular cross-section (Jones and Kocher, 1995) was revised to account for the minimum flighting height that could effectively unload particles with a known average smallest diameter. A minimum flighting height that was about 64% of the average smallest diameter of the particles was experimentally determined to obtain mean slopes of the top surface of the material not significantly different from zero for screened soybeans. A linear taper that best fit the square root curve for the inside diameter of the auger was …