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Novel Modeling Techniques For Tumor Diagnostics Using Pulsed Laser Sources, Mohamed Sakami, Kunal Mitra, Tuan Vo-Dinh

Biomedical Engineering and Sciences Faculty Publications

In this paper, a two-dimensional transient radiation transport algorithm is developed to analyze short pulse laser transport through a tissue medium having tumors and inhomogeneities imbedded in it. Short pulse probing techniques have distinct advantages over conventional very large pulse width or cw lasers primarily due to the additional information conveyed about the tissue interior by the temporal variation of the observed signal. The distinct feature is the multiple scattering induced temporal signatures that persists for time periods greater than the duration of the source pulse and is a function of the source pulse width, the scattering/absorbing properties and nature …