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Full-Text Articles in Biomedical Engineering and Bioengineering
A General-Purpose Software Platform For Closed-Loop Neuromodulation, William Engelhardt
A General-Purpose Software Platform For Closed-Loop Neuromodulation, William Engelhardt
McKelvey School of Engineering Theses & Dissertations
Implementing closed-loop neuromodulation therapies is a challenging and expensive endeavor. It requires developing software capable of acquiring signals from a bio-signal amplifier, analysis of these signals, and initiation of precisely timed stimulation, all of which need to be accomplished in real-time with very low latency. Developing this software is difficult, as it requires a wide range of expertise ranging from interfacing with hardware to real-time signal processing. Even when successfully implementing such a system for one set of hardware, it often then only works within the laboratory that conceived it. This is because of the inherent heterogeneity in the devices …
Brain-Computer Interfaces Using Electrocorticography And Surface Stimulation, Jesse Wheeler
Brain-Computer Interfaces Using Electrocorticography And Surface Stimulation, Jesse Wheeler
McKelvey School of Engineering Theses & Dissertations
The brain connects to, modulates, and receives information from every organ in the body. As such, brain-computer interfaces (BCIs) have vast potential for diagnostics, medical therapies, and even augmentation or enhancement of normal functions. BCIs provide a means to explore the furthest corners of what it means to think, to feel, and to act—to experience the world and to be who you are. This work focuses on the development of a chronic bi-directional BCI for sensorimotor restoration through the use of separable frequency bands for recording motor intent and providing sensory feedback via electrocortical stimulation. Epidural cortical surface electrodes are …