Biomedical Engineering and Bioengineering Commons^™

Analyzing Heat Generated From Electro-Osmotic Flow Utilizing Computational Fluid Dynamics, Jordan Elizabeth Grothe

Honors Thesis

Without extensive vascularization, the transfer of fluid and nutrients through human tissue is limited to diffusion and weak interstitial flow. Electroosmosis, or the flow of fluid driven by an electrical field, has become a promising solution. Scientists have begun applying electricity to human tissue to promote stronger interstitial flow; however, optimization of this process has proven to be a challenge due to ohmic heating. Cells function within a small range of temperatures and exposure to voltages exceeding the threshold will cause cells to degrade and die prematurely. This research seeks to better understand and quantify the range of voltage where …