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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Microengineering The Neural Tube, Christopher Demers Aug 2015

Microengineering The Neural Tube, Christopher Demers

Electronic Theses and Dissertations

Early embryonic development is a complex and highly regulated orchestra of instructive cues that collectively guide naïve stem cells towards progressively more specialized fates. In the neural tube, the precursor structure to the brain and spinal cord, these signals emanate from ‘organizing centers’ surrounding the neural tube. These organizing centers send out soluble cues or morphogens that diffuse tens to hundreds of microns to recipient cells residing in the neural tube. Re-creating this dynamic landscape of cues in vitro is impossible using standard cell culture tools and techniques. However, microfluidics is perfectly suited to fill this gap, allowing precise control …


Investigating The Optimization Of Zebrafish (Danio Rerio) Dechorionation For High-Throughput Applications In Influenza Research, Thomas Hoffmann May 2015

Investigating The Optimization Of Zebrafish (Danio Rerio) Dechorionation For High-Throughput Applications In Influenza Research, Thomas Hoffmann

Honors College

No abstract provided.


Physical Properties Of Iron Oxide Nanoparticles, Nicklaus Carter Apr 2015

Physical Properties Of Iron Oxide Nanoparticles, Nicklaus Carter

Honors College

Magnetic Resonance Imaging (MRI) relies heavily on contrast agents such that diagnosis of various diseases can be made with increased confidence. Current contrast agents for MRI depend on various chelated molecules composed of a toxic gadolinium ion, Gd3+. In 2006, a discovery was made connecting Nephrogenic Systemic Fibrosis (NSF) and these gadolinium based contrast agents (GBCAs). The connection between life threatening NSF and GBCAs stems from patients with pre-existing kidney malfunctions. It has been proposed that an alternative agent such as iron oxide nanoparticles (IONPs) be investigated. These IONPs theoretically will have similar responses in efficiency of improving …


Technology And Aging: An Emerging Research And Development Sector In Maine, Carol H. Kim, David Neivandt, Lenard W. Kaye, Jennifer A. Crittenden Jan 2015

Technology And Aging: An Emerging Research And Development Sector In Maine, Carol H. Kim, David Neivandt, Lenard W. Kaye, Jennifer A. Crittenden

Maine Policy Review

The authors discuss the importance of research for developing products and services that cater to the needs of a rapidly growing aging population and provide examples of projects underway at the University of Maine. Products designed to improve and protect older adult health and well-being represent a significant opportunity for economic growth in Maine.