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Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
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- Alzheimer’s Disease (AD) (1)
- Ambroxol (1)
- Amygdala (1)
- FT-IR (1)
- Gaussian Map (1)
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- Gaussian curvature (1)
- Gaussian shape operator (1)
- Hippocampus (1)
- Magnetic Resonance Imaging (MRI) (1)
- Mean curvature (1)
- Non-synonymous single nucleotide variants (nsSNVs) Pathogenic Neutral Integrated rules classifier ISTJRip ISTJ48 ISTRF ISTSVM VaribenchSelectedPure (1)
- Schiff base (1)
- Shape features (1)
- Support Vector Machine (SVM). (1)
- Thermal analyses and Antimicrobial activity. (1)
- Tissue engineering and regenerative medicine; biopolymers; nanofabrication techniques; additive manufacturing; rapid prototyping; customized therapy 3D scaffolds (1)
- UV–Vis (1)
Articles 1 - 4 of 4
Full-Text Articles in Biomedical Engineering and Bioengineering
Integrated Rules Classifier For Predicting Pathogenic Non-Synonymous Single Nucleotide Variants In Human, Ahmed Barakat Hosseny, Marwa Said Hassan, A A. Shalan, Shymaa Khamis, M I. Dessouky
Integrated Rules Classifier For Predicting Pathogenic Non-Synonymous Single Nucleotide Variants In Human, Ahmed Barakat Hosseny, Marwa Said Hassan, A A. Shalan, Shymaa Khamis, M I. Dessouky
Basic Science Engineering
The most prevalent kind of genetic variants in humans are non-synonymous single nucleotide variants (nsSNVs). Several prediction tools have been launched to forecast the effect of amino acid substitutes on human protein function. These tools sort variants as pathogenic or neutral. We developed an Integrated Rules Classifier (Integration Score through JRip “ISTJRip”), which integrates the four individual tools that are publicly available; iFish, Mutation Assessor, FATHMM, and SIFT-based on the JRip machine learning technique. Additionally, we compared the ISTJRip approach with the other three created integration classifiers; Integration Score through J48 “ISTJ48”, Integration Score through RF “ISTRF”, and Integration …
Hierarchical Based Classifcation Method Based On Fusion Ofgaussian Map Descriptors Foralzheimer Diagnosis Using T1‑Weighted Magnetic Resonance Imaging, Nourhan Zayed, Shereen E. Morsy, Inas A. Yassine
Hierarchical Based Classifcation Method Based On Fusion Ofgaussian Map Descriptors Foralzheimer Diagnosis Using T1‑Weighted Magnetic Resonance Imaging, Nourhan Zayed, Shereen E. Morsy, Inas A. Yassine
Mechanical Engineering
Alzheimer’s disease (AD) is considered one of the most spouting elderly diseases. In 2015, AD is reported the US’s sixth cause of death. Substantially, non-invasive imaging is widely employed to provide biomarkers supporting AD screening, diagnosis, and progression. In this study, Gaussian descriptors-based features are proposed to be efcient new biomarkers using Magnetic Resonance Imaging (MRI) T1-weighted images to diferentiate between Alzheimer’s disease (AD), Mild Cognitive Impairment (MCI), and Normal controls (NC). Several Gaussian map-based features are extracted such as Gaussian shape operator, Gaussian curvature, and mean curvature. The aforementioned features are then introduced to the Support Vector Machine (SVM). …
A Review Of 3d Polymeric Scaffolds For Bone Tissue Engineering: Principles, Fabrication Techniques, Immunomodulatory Roles, And Challenges, Hassan Nageh, Ahmed G. Abdelaziz, Sara M. Abdo, Mohga S. Abdalla, Asmaa A. Amer, Abdalla Abdal-Hay, Ahmed Barhoum
A Review Of 3d Polymeric Scaffolds For Bone Tissue Engineering: Principles, Fabrication Techniques, Immunomodulatory Roles, And Challenges, Hassan Nageh, Ahmed G. Abdelaziz, Sara M. Abdo, Mohga S. Abdalla, Asmaa A. Amer, Abdalla Abdal-Hay, Ahmed Barhoum
Nanotechnology Research Centre
Over the last few years, biopolymers have attracted great interest in tissue engineering and regenerative medicine due to the great diversity of their chemical, mechanical, and physical properties for the fabrication of 3D scaffolds. This review is devoted to recent advances in synthetic and natural polymeric 3D scaffolds for bone tissue engineering (BTE) and regenerative therapies. The review comprehensively discusses the implications of biological macromolecules, structure, and composition of polymeric scaffolds used in BTE. Various approaches to fabricating 3D BTE scaffolds are discussed, including solvent casting and particle leaching, freeze-drying, thermally induced phase separation, gas foaming, electrospinning, and sol–gel techniques. …
Preparation, Characterization And Biological Activity Evaluation Of Some Metal Complexes From Novel Schiff Bases Based On Ambroxol Drug, Hoda Ahmed, Walaa H. Mahmoud, Mostafa M.H Khalil, Gehad G. Mohamed, Mostafa A. Radwan
Preparation, Characterization And Biological Activity Evaluation Of Some Metal Complexes From Novel Schiff Bases Based On Ambroxol Drug, Hoda Ahmed, Walaa H. Mahmoud, Mostafa M.H Khalil, Gehad G. Mohamed, Mostafa A. Radwan
Chemical Engineering
Novel Schiff bases were prepared as the condensation product of reaction of 2- hydroxybenzaldehyde and ambroxol drug (H2L1) and the second one from the reaction of 2-quinoline carbaldehyde with ambroxol (HL2). The synthesized Schiff basses were acted as a tridentate ligand for the preparation of new complexes through reaction with the metal ions of Cd(II) and Sn(II). The newly prepared Schiff bases and their metal complexes were characterized using some physicochemical techniques including elemental analysis, FT-IR, UV–Vis, mass spectrometry, conducti-metric measurements as well as thermal analyses (TGA/DTG),. On the basis of these studies, an octahedral geometry for both Cd(II) and …