Biomedical Engineering and Bioengineering Commons^™

Evaluating The Viscoelastic Properties Of Alligator Skin Gelatin, Alligel, Compared To Mammalian And Fish Gelatins, Sarah E. Jimenez

Honors Theses

No abstract provided.

The Synthesis And Characterization Of Ionic Liquids Using Nitrogen-Based Cations For Transdermal Delivery, Jo Galloway

Honors Theses

The purpose of this research was to explore the synthesis mechanisms of water-soluble ionic liquids with nitrogen-containing cationic bases for future use in transdermal drug delivery and forensic science applications. Ionic liquids are salts with an organic cation and either an organic or inorganic anion. They have asymmetric structures, which means that the molecules don’t pack together as neatly as other salts do, therefore, they don’t crystallize as easily, and their melting points are lower. Ionic liquids have melting points below 100°C, and many are liquid at room temperature. Mechanistic studies reveal that the potency of ILs in enhancing transdermal …

Evaluation Of Triple Negative Breast Cancer Tumor Matrix, Alejandra Ham

Honors Theses

No abstract provided.

Nanoparticle Quantification And Distribution On Fluorescently Coated Angioplasty Balloons, Allison Dobson Zieschang

Honors Theses

No abstract provided.

Challenges Of Constructing Entrainment Map For Arbitrary Circadian Models, Yuxuan (Nelson) Wu

Honors Theses

The entrainment map, developed by Dr.Diekman and Dr.Bose, is claimed to be a 1-dimensional map that produces a better prediction for phase-locking than methods than the phase response curve for circadian models. In his paper, he constructs the entrainment map for the two-dimensional circadian model, the Novak-Tyson model, and the other two higher-dimensional circadian models. For this thesis, we concentrate on exploring if it is viable to construct the entrainment map for other circadian models that are not included in his paper: the Becker-Weimann model and the Relogio model. In addition, we discuss the challenges of constructing the entrainment map …

Analyzing The Effects Of E-Hook Peptides On Kinesin-1, Ashton Ward Murrah, Baylee Hope Howard

Honors Theses

Cancer is the second leading cause of death in the United States. Cancerous growth is a result of oncogenes, or mutated genes that increase the rate of cell division in an uncontrolled manner. Cell division, which consists of mitosis and cytokinesis phases, is dependent upon the active movement of kinesin motor proteins along microtubules to rearrange the cytoskeleton for equitable distribution of genetic material to daughter cells. As kinesins are vital to this process, if we could prevent kinesin from binding to the microtubules, cell division would cease.

The goal of this study is to develop a method to prevent …

Surface-Eroding Drug Delivery Films For Sequential And/Or Intermittent Release Of Psychoactive Drugs, Jason Price

Honors Theses

ABSTRACT JASON BLAKE PRICE: Surface-Eroding Drug Delivery Films for Sequential and/or

Intermittent Release of Psychoactive Drugs For patients with psychiatric diseases, adherence to medication schedules, medication

errors, and abuse are common issues. Promising new forms of therapy for these patients, such as micro-dosed lysergic acid diethylamide (LSD), where patients receive 10-20% of a full dose every third day, present further drug delivery challenges. Sequential or intermittent release of drugs from an implanted device could ensure long-term drug compliance, automate drug dosing during the life of the implant, and eliminate potential for abuse and medication errors. To this end, we generated …

Velocity Distribution And Stress Analysis In A Continuous Exchange Cell-Free Protein Synthesis System, Grace Nguyen

Honors Theses

No abstract provided.

Development And Mechanical Characterization Of A Composite Biomaterial Made From Agricultural Waste Reinforcement In A Fungal Mycelium Matrix., John Adam Howe

Honors Theses

No abstract provided.

Investigatin Actin-Myosin Mechanics To Model Heart Disease Using Fluorescence Microscopy And Optical Trapping, Justin Edward Reynolds

Honors Theses

Hypertrophic cardiomyopathy (HCM) is a hereditary disease in which the myocardium becomes hypertrophied, making it more difficult for the heart to pump blood. HCM is commonly caused by a mutation in the β-cardiac myosin II heavy chain. Myosin is a motor protein that facilitates muscle contraction by converting chemical energy from ATP hydrolysis into mechanical work and concomitantly moving along actin filaments. Optical tweezers have been used previously to analyze single myosin biophysical properties; however, myosin does not work as a single unit within the heart. Multiple myosin interacts to displace actin filaments and do not have the same properties …

Review Of Naturally Occurring Ammonia In Groundwater And Its Effect On Using Chloramines For Drinking Water Disinfection In Louisiana, Athena Lindsay

Honors Theses

No abstract provided.

3d-Printed Culture Plate Insert With Agarose Barrier For The Evaluation Of Stem-Cancer Cell Signaling., Erika M. Lewis

Honors Theses

No abstract provided.

Implementation Of A Particle Image Velocimetry System For Evaluation Of Microfluidic Chip Flows, Sheila Mallenahalli

Honors Theses

No abstract provided.

Dynamic Classification Of Moisture Stress Using Canopy And Leaf Temperature Responses To A Step Changes Of Incident Radiation, Erin E. Stevens, George E. Meyer, Ellen T. Paparozzi

Honors Theses

Environmental conditions affect plant productivity and understanding how plants respond to drought stress can be measured in different ways. This study focused on measuring leaf response time to induced water stress. Leaf response time to a step increase and step decrease in radiation was computed for four species of well-watered and water-stressed plants in a controlled environment. The canopy temperature was measured with an infrared thermometer and a thermal imaging camera. Thermal images were analyzed to determine the average temperature of a selected single, unobstructed leaf at the top of the canopy. Both the canopy response time and the single …

Pentaerythritol Triacrylate-Co-Trimethylolpropane Nanocomposite Scaffolds As Osteogenic Components For Bone Tissue Engineering, Mollie Marie Smoak

Honors Theses

No abstract provided.

Zein Nanoparticle Interaction With Soybean Plants, Kurt Ristroph

Honors Theses

No abstract provided.

Aconitic Acid, Glycerol And Cinnamic Acid Polyester Characterization For Bone Tissue Engineering, Katie Joanna Hogan

Honors Theses

No abstract provided.

Synthesis, Functionalization, And Characterization Of Metallic And Organic Nanoparticles For Biomedical Applications, Christopher Brian Sylvester

Honors Theses

No abstract provided.

In Vivo Evaluation Of An Automated Pressure Sore Reducer, Linda J. Cross

Honors Theses

No abstract provided.

Cryoprotectant Loading In A Microchannel, Shelby Pursley

Honors Theses

No abstract provided.

Computational Modeling Of Drug Release From Bone Scaffolds, Corey Landry

Honors Theses

No abstract provided.

Adhesion Of Jurkat Cells In Defined Media And Substrates, Sarah De Leo

Honors Theses

No abstract provided.

Modeling Electric Fields In Microfluidic Devices, Micah Fincher

Honors Theses

No abstract provided.