Biomedical Engineering and Bioengineering Commons^™

Estimating Effective Connectivity From Fmri Data Using Factor-Based Subspace Autoregressive Models, Chee-Ming Ting Phd, Abd-Krim Seghouane Phd, Sh-Hussain Salleh Phd, Alias M. Noor Phd

Chee-Ming Ting

Probabilistic Uncertainty Quantification And Experiment Design For Nonlinear Models: Applications In Systems Biology, Vu Cao Duy Thien Dinh

Open Access Dissertations

Despite the ever-increasing interest in understanding biology at the system level, there are several factors that hinder studies and analyses of biological systems. First, unlike systems from other applied fields whose parameters can be effectively identified, biological systems are usually unidentifiable, even in the ideal case when all possible system outputs are known with high accuracy. Second, the presence of multivariate bifurcations often leads the system to behaviors that are completely different in nature. In such cases, system outputs (as function of parameters/inputs) are usually discontinuous or have sharp transitions across domains with different behaviors. Finally, models from systems biology …

Estimation Of High-Dimensional Brain Connectivity From Fmri Data Using Factor Modeling, Chee-Ming Ting Phd, Abd-Krim Seghouane, Sh-Hussain Salleh, Alias M. Noor

Chee-Ming Ting

We consider identifying effective connectivity of brain networks from fMRI time series. The standard vector autoregressive (VAR) models fail to give reliable network estimates, typically involving very large number of nodes. This paper adopts a dimensionality reduction approach based on factor modeling, to enable effective and efficient high-dimensional VAR analysis of large network connectivity. We derive a subspace VAR (SVAR) model from the factor model (FM) in which the observations are driven by a lower dimensional subspace of common latent factors, following an autoregressive dynamics. We consider the principal components (PC) method which can produce consistent estimators for the FM, …

Sensitivity Analysis Of A Leaf Photosynthesis-Stomatal Resistance Model, Gabriel A. Garcia

Chancellor’s Honors Program Projects

No abstract provided.

Sensitivity Analysis Of A Photosynthesis-Stomatal Resistance Model, Gabriel A. Garcia

EURēCA: Exhibition of Undergraduate Research and Creative Achievement

Abstract/Poster