Biomedical Engineering and Bioengineering Commons^™

Design And Basic Verification Of A Discrete Event Simulator For Glucose Metabolism In Human Beings, Elizabeth Andrews

Theses and Dissertations

This thesis describes the design and basic verification of a discrete event simulator for glucose metabolism in human beings. The simulator implements the glucose metabolism related behavior of various organs in the human body and tracks the blood plasma glucose level as the human body goes through a sequence of diet and exercise events. The simulator can mimic insulin resistance in various organs as well as the loss of insulin production in the pancreas and the adverse impact of these changes on the metabolic behavior of various organs. Thus, the simulator can serve as a model for people with diabetes. …

Quantitative Optical Studies Of Oxidative Stress In Rodent Models Of Eye And Lung Injuries, Zahra Ghanian

Theses and Dissertations

Optical imaging techniques have emerged as essential tools for reliable assessment of organ structure, biochemistry, and metabolic function. The recognition of metabolic markers for disease diagnosis has rekindled significant interest in the development of optical methods to measure the metabolism of the organ.

The objective of my research was to employ optical imaging tools and to implement signal and image processing techniques capable of quantifying cellular metabolism for the diagnosis of diseases in human organs such as eyes and lungs. To accomplish this goal, three different tools, cryoimager, fluorescent microscope, and optical coherence tomography system were utilized to study the …