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Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
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Articles 1 - 30 of 42
Full-Text Articles in Biomedical Engineering and Bioengineering
Modeling Synergistic Effects Of Integrin And Tgf-Beta Signaling In Epithelial Mesenchymal Transition, Prerak Thakkar
Modeling Synergistic Effects Of Integrin And Tgf-Beta Signaling In Epithelial Mesenchymal Transition, Prerak Thakkar
Biology and Medicine Through Mathematics Conference
No abstract provided.
La1-Xsrxcoo3 Perovskite Nanomaterial: Synthesis, Characterization, And Its Biomedical Application, Adhira Tippur, Anyet Shohag, Luke Franco, Ahmed Touhami, Swati Mohan, Mohammed Uddin
La1-Xsrxcoo3 Perovskite Nanomaterial: Synthesis, Characterization, And Its Biomedical Application, Adhira Tippur, Anyet Shohag, Luke Franco, Ahmed Touhami, Swati Mohan, Mohammed Uddin
Research Symposium
Early cancer detection is paramount for effective treatment and potential cures. This research explores the application of perovskite materials, specifically Sr2+-doped Lanthanum Cobaltite (La1-xSrxCoO3) nanomaterials, in cancer detection, with a focus on rats as an experimental model. The ferroelectric nature of these materials, synthesized through a combination of sol-gel and molten-salt processes, was examined at varying Sr2+ doping levels (1-20 wt%). Rigorous characterization, employing X-ray diffraction and scanning electron microscopy, confirmed the uniform morphology of nano cubes, laying the foundation for subsequent investigations. The magnetic properties of the perovskite nanoparticles were probed, suggesting their potential as a diagnostic tool for …
Computational Modeling Using A Novel Continuum Approach Coupled With Pathway-Informed Neural Networks To Optimize Dynein-Mediated Centrosome Positioning In Polarized Cells, Arkaprovo Ghosal, Padmanabhan Seshaiyar Dr., Adriana Dawes Dr., General Genomics Inc.
Computational Modeling Using A Novel Continuum Approach Coupled With Pathway-Informed Neural Networks To Optimize Dynein-Mediated Centrosome Positioning In Polarized Cells, Arkaprovo Ghosal, Padmanabhan Seshaiyar Dr., Adriana Dawes Dr., General Genomics Inc.
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling Epithelial-Mesenchymal Transition In A 3d Multicellular Model Of Tgf-Β1 Signaling, Kristin Kim, Chris Lemmon
Modeling Epithelial-Mesenchymal Transition In A 3d Multicellular Model Of Tgf-Β1 Signaling, Kristin Kim, Chris Lemmon
Biology and Medicine Through Mathematics Conference
No abstract provided.
Enhancement Of Deep Learning Protein Structure Prediction, Ruoming Shen
Enhancement Of Deep Learning Protein Structure Prediction, Ruoming Shen
Modeling, Simulation and Visualization Student Capstone Conference
Protein modeling is a rapidly expanding field with valuable applications in the pharmaceutical industry. Accurate protein structure prediction facilitates drug design, as extensive knowledge about the atomic structure of a given protein enables scientists to target that protein in the human body. However, protein structure identification in certain types of protein images remains challenging, with medium resolution cryogenic electron microscopy (cryo-EM) protein density maps particularly difficult to analyze. Recent advancements in computational methods, namely deep learning, have improved protein modeling. To maximize its accuracy, a deep learning model requires copious amounts of up-to-date training data.
This project explores DeepSSETracer, a …
The Effects Of Demographics And Risk Factors On The Morphological Characteristics Of Human Femoropopliteal Arteries, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy
The Effects Of Demographics And Risk Factors On The Morphological Characteristics Of Human Femoropopliteal Arteries, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy
UNO Student Research and Creative Activity Fair
Background: Disease of the lower extremity arteries (Peripheral Arterial Disease, PAD) is associated with high morbidity and mortality. During disease development, the arteries adapt by changing their diameter, wall thickness, and residual deformations, but the effects of demographics and risk factors on this process are not clear.
Methods: Superficial femoral arteries from 736 subjects (505 male, 231 female, 12 to 99 years old, average age 51±17.8 years) and the associated demographic and risk factor variables were used to construct machine learning (ML) regression models that predicted morphological characteristics (diameter, wall thickness, and longitudinal opening angle resulting from the …
Time Evolution Is A Source Of Bias In The Wolf Algorithm For Largest Lyapunov Exponents, Kolby Brink, Tyler Wiles, Nicholas Stergiou, Aaron Likens
Time Evolution Is A Source Of Bias In The Wolf Algorithm For Largest Lyapunov Exponents, Kolby Brink, Tyler Wiles, Nicholas Stergiou, Aaron Likens
UNO Student Research and Creative Activity Fair
Human movement is inherently variable by nature. One of the most common analytical tools for assessing movement variability is the largest Lyapunov exponent (LyE) which quantifies the rate of trajectory divergence or convergence in an n-dimensional state space. One popular method for assessing LyE is the Wolf algorithm. Many studies have investigated how Wolf’s calculation of the LyE changes due to sampling frequency, filtering, data normalization, and stride normalization. However, a surprisingly understudied parameter needed for LyE computation is evolution time. The purpose of this study is to investigate how the LyE changes as a function of evolution time …
2d Respiratory Sound Analysis To Detect Lung Abnormalities, Rafia Sharmin Alice, Kc Santosh
2d Respiratory Sound Analysis To Detect Lung Abnormalities, Rafia Sharmin Alice, Kc Santosh
SDSU Data Science Symposium
Abstract. In this paper, we analyze deep visual features from 2D data representation(s) of the respiratory sound to detect evidence of lung abnormalities. The primary motivation behind this is that visual cues are more important in decision-making than raw data (lung sound). Early detection and prompt treatments are essential for any future possible respiratory disorders, and respiratory sound is proven to be one of the biomarkers. In contrast to state-of-the-art approaches, we aim at understanding/analyzing visual features using our Convolutional Neural Networks (CNN) tailored Deep Learning Models, where we consider all possible 2D data such as Spectrogram, Mel-frequency Cepstral Coefficients …
Producing And Measuring Oscillatory Shear In A Novel Microfluidic Chip, Sanaz Lordfard, Daniel Lorusso, Tamie L. Poepping, Hristo N Nikolov, Kayla Soon, Stephen Sims, Jeffrey Dixon, David Holdsworth
Producing And Measuring Oscillatory Shear In A Novel Microfluidic Chip, Sanaz Lordfard, Daniel Lorusso, Tamie L. Poepping, Hristo N Nikolov, Kayla Soon, Stephen Sims, Jeffrey Dixon, David Holdsworth
Undergraduate Student Research Internships Conference
Purpose: To demonstrate the effectiveness of a novel microfluidic device mimicking oscillatory blood flow, allowing cell biologists to examine how endothelial cells respond to a range of oscillatory shear stress levels.
Methods: The microfluidic chip consists of a circular-shaped reservoir, leading to a rectangular channel that is examined under a microscope. The plunger is connected to a speaker system and oscilloscope, allowing the plunger to apply a range of frequencies (5-60Hz) and voltages (5-10 V, leading to a variety in oscillation amplitudes) to the reservoir region. 1.1 um fluorescent particles diluted in distilled water were used for tracking. Processing was …
Optimal Design Of Bacterial Carpets For Fluid Pumping, Minghao W. Rostami, Weifan Liu, Amy Buchmann, Eva Strawbridge, Longhua Zhao
Optimal Design Of Bacterial Carpets For Fluid Pumping, Minghao W. Rostami, Weifan Liu, Amy Buchmann, Eva Strawbridge, Longhua Zhao
Biology and Medicine Through Mathematics Conference
No abstract provided.
Two-Stage Transfer Learning For Facial Expression Classification In Children, Gregory Hubbard, Megan Witherow, Khan Iftekharuddin
Two-Stage Transfer Learning For Facial Expression Classification In Children, Gregory Hubbard, Megan Witherow, Khan Iftekharuddin
Undergraduate Research Symposium
Studying facial expressions can provide insight into the development of social skills in children and provide support to individuals with developmental disorders. In afflicted individuals, such as children with Autism Spectrum Disorder (ASD), atypical interpretations of facial expressions are well-documented. In computer vision, many popular and state-of-the-art deep learning architectures (VGG16, EfficientNet, ResNet, etc.) are readily available with pre-trained weights for general object recognition. Transfer learning utilizes these pre-trained models to improve generalization on a new task. In this project, transfer learning is implemented to leverage the pretrained model (general object recognition) on facial expression classification. Though this method, the …
Reducing Loading On The Contralateral Limb Using Human-In-The-Loop Optimization, Siena Senatore
Reducing Loading On The Contralateral Limb Using Human-In-The-Loop Optimization, Siena Senatore
UNO Student Research and Creative Activity Fair
In most everyday activities, we head towards a specific goal by updating our choices for a more direct path. However, there are specific clinical tasks where taking the direct path is more challenging. Clinical investigations of optimizing a prosthesis involve the assessment of multiple parameter settings through trial and error rather than goal-directed optimization. We investigate if a human-in-the-loop optimization algorithm can guide manual alterations to a prosthesis-simulating device to reduce the ground reaction force on the contralateral limb. In most participants, the optimal condition reduced the loading rate on the contralateral limb compared to the initial condition tested. These …
Design And Development Of Software With A Graphical User Interface To Display And Convert Multiple Microscopic Histology Images, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy
Design And Development Of Software With A Graphical User Interface To Display And Convert Multiple Microscopic Histology Images, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy
UNO Student Research and Creative Activity Fair
Histological images are widely used to assess the microscopic anatomy of biological tissues. Recent advancements in image analysis allow the identification of structural features on histological sections that can help advance medical device development, brain and cancer research, drug discovery, vascular mechanobiology, and many other fields. Histological slide scanners create images in SVS and TIFF formats that were designed to archive image blocks and high-resolution textual information. Because these formats were primarily intended for storage, they are often not compatible with conventional image analysis software and require conversion before they can be used in research. We have developed a user-friendly …
Understanding The Effect Of Adaptive Mutations On The Three-Dimensional Structure Of Rna, Justin Cook
Understanding The Effect Of Adaptive Mutations On The Three-Dimensional Structure Of Rna, Justin Cook
Undergraduate Research and Scholarship Symposium
Single-nucleotide polymorphisms (SNPs) are variations in the genome where one base pair can differ between individuals.1 SNPs occur throughout the genome and can correlate to a disease-state if they occur in a functional region of DNA.1According to the central dogma of molecular biology, any variation in the DNA sequence will have a direct effect on the RNA sequence and will potentially alter the identity or conformation of a protein product. A single RNA molecule, due to intramolecular base pairing, can acquire a plethora of 3-D conformations that are described by its structural ensemble. One SNP, rs12477830, which …
Multidisciplinary Education And Research In Biomathematics For Solving Global Challenges, Padmanabhan Seshaiyer
Multidisciplinary Education And Research In Biomathematics For Solving Global Challenges, Padmanabhan Seshaiyer
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Predicting Tgf-Β-Induced Epithelial-Mesenchymal Transition Using Data Assimilation, Mario J. Mendez, Matthew J. Hoffman, Elizabeth M. Cherry, Dr. Christopher Lemmon, Seth Weinberg
Predicting Tgf-Β-Induced Epithelial-Mesenchymal Transition Using Data Assimilation, Mario J. Mendez, Matthew J. Hoffman, Elizabeth M. Cherry, Dr. Christopher Lemmon, Seth Weinberg
Biology and Medicine Through Mathematics Conference
No abstract provided.
Age Dependent Regulation Of Cardiac Sodium Channel Gain Of Function, Madison Nowak, David Ryan King, Steven Poelzing, Seth Weinberg
Age Dependent Regulation Of Cardiac Sodium Channel Gain Of Function, Madison Nowak, David Ryan King, Steven Poelzing, Seth Weinberg
Biology and Medicine Through Mathematics Conference
No abstract provided.
Coupled Influence Of Heart Rate Variability And Subcellular Calcium Heterogeneity On Cardiac Electromechanical Dynamics, Vrishti M. Phadumdeo, Seth H. Weinberg Ph.D
Coupled Influence Of Heart Rate Variability And Subcellular Calcium Heterogeneity On Cardiac Electromechanical Dynamics, Vrishti M. Phadumdeo, Seth H. Weinberg Ph.D
Biology and Medicine Through Mathematics Conference
No abstract provided.
Immunofluorescence Image Feature Analysis And Clustering Pipeline For Distinguishing Epithelial-Mesenchymal Transition, Shreyas Hirway, Nadiah Hassan, Dr. Christopher Lemmon, Dr. Seth Weinberg
Immunofluorescence Image Feature Analysis And Clustering Pipeline For Distinguishing Epithelial-Mesenchymal Transition, Shreyas Hirway, Nadiah Hassan, Dr. Christopher Lemmon, Dr. Seth Weinberg
Biology and Medicine Through Mathematics Conference
No abstract provided.
Fluoride Removal From Water Using A 3d Printed Calcium Carbonate Filter, Sophia Bakar, David Kahler, Benjamin S. Goldschmidt
Fluoride Removal From Water Using A 3d Printed Calcium Carbonate Filter, Sophia Bakar, David Kahler, Benjamin S. Goldschmidt
Undergraduate Research and Scholarship Symposium
Groundwater containing high concentrations of fluoride is the most common source of drinking water in rural areas in parts of east Africa, India, and China. The elevated levels of fluoride cause skeletal and dental fluorosis, which is the weakening and decay of bone structures due to the leeching of calcium from the body as calcium and fluoride bond by the process of adsorption. Over 150 million people are suffering from some form of fluorosis due to the consumption of groundwater. Calcium carbonate has been demonstrated to influence fluoride removal in several forms. To make fluoride removal a cost-effective and user-friendly …
Quantifying Iron Overload Using Mri, Active Contours, And Convolutional Neural Networks, Andrea Sajewski, Stacey Levine
Quantifying Iron Overload Using Mri, Active Contours, And Convolutional Neural Networks, Andrea Sajewski, Stacey Levine
Undergraduate Research and Scholarship Symposium
Iron overload, a complication of repeated blood transfusions, can cause tissue damage and organ failure. The body has no regulatory mechanism to excrete excess iron, so iron overload must be closely monitored to guide therapy and measure treatment response. The concentration of iron in the liver is a reliable marker for total body iron content and is now measured noninvasively with magnetic resonance imaging (MRI). MRI produces a diagnostic image by measuring the signals emitted from the body in the presence of a constant magnetic field and radiofrequency pulses. At each pixel, the signal decay constant, T2*, can be calculated, …
Estimating Variations In Metabolic Cost Within The Stride Cycle During Level And Uphill Walking, Arash Mohammadzadeh Gonabadi
Estimating Variations In Metabolic Cost Within The Stride Cycle During Level And Uphill Walking, Arash Mohammadzadeh Gonabadi
UNO Student Research and Creative Activity Fair
Indirect calorimetry provides the average cost of a stride cycle and prevents from identifying which part of the gait cycle causes increased metabolic cost in patients, however, recent simulation methods allow estimating the time profile of metabolic cost within the stride cycle. In this study, we compare the estimations of the time profile of the metabolic cost of two simulation methods for level and uphill walking. We used kinematic, kinetic and electromyography data from level and uphill walking (one participant) to estimate the time profiles of metabolic cost using the muscle-level metabolic model of Umberger using electromyography and kinematic data …
Using Eeg-Validated Music Emotion Recognition Techniques To Classify Multi-Genre Popular Music For Therapeutic Purposes, Dejoy Shastikk Kumaran
Using Eeg-Validated Music Emotion Recognition Techniques To Classify Multi-Genre Popular Music For Therapeutic Purposes, Dejoy Shastikk Kumaran
The International Student Science Fair 2018
Music is observed to possess significant beneficial effects to human mental health, especially for patients undergoing therapy and older adults. Prior research focusing on machine recognition of the emotion music induces by classifying low-level music features has utilized subjective annotation to label data for classification. We validate this approach by using an electroencephalography-based approach to cross-check the predictions of music emotion made with the predictions from low-level music feature data as well as collected subjective annotation data. Collecting 8-channel EEG data from 10 participants listening to segments of 40 songs from 5 different genres, we obtain a subject-independent classification accuracy …
Using Eeg-Validated Music Emotion Recognition Techniques To Classify Multi-Genre Popular Music For Therapeutic Purposes, Dejoy Shastikk Kumaran
Using Eeg-Validated Music Emotion Recognition Techniques To Classify Multi-Genre Popular Music For Therapeutic Purposes, Dejoy Shastikk Kumaran
The International Student Science Fair 2018
Music is observed to possess significant beneficial effects to human mental health, especially for patients undergoing therapy and older adults. Prior research focusing on machine recognition of the emotion music induces by classifying low-level music features has utilized subjective annotation to label data for classification. We validate this approach by using an electroencephalography-based approach to cross-check the predictions of music emotion made with the predictions from low-level music feature data as well as collected subjective annotation data. Collecting 8-channel EEG data from 10 participants listening to segments of 40 songs from 5 different genres, we obtain a subject-independent classification accuracy …
Regulation Of Cellular Patterning Through The Extracellular Matrix, Lewis Scott, Lauren Griggs, Vani Narayanan, Daniel Conway Phd, Seth H. Weinberg Phd, Christopher Lemmon Phd
Regulation Of Cellular Patterning Through The Extracellular Matrix, Lewis Scott, Lauren Griggs, Vani Narayanan, Daniel Conway Phd, Seth H. Weinberg Phd, Christopher Lemmon Phd
Biology and Medicine Through Mathematics Conference
No abstract provided.
Intercellular Sodium Nanodomain Signaling Regulates Repolarization In Cardiac Tissue, Madison Nowak, Seth Weinberg Ph.D.
Intercellular Sodium Nanodomain Signaling Regulates Repolarization In Cardiac Tissue, Madison Nowak, Seth Weinberg Ph.D.
Biology and Medicine Through Mathematics Conference
No abstract provided.
Chemotherapeutic Drug Cytotoxicity Measurement With A 3d Biomimetic Microfluidic Device And Computational Fluid Dynamics Model, Maryam Moarefian, Caroline Jones, Luke Achenie, Danesh Tafti
Chemotherapeutic Drug Cytotoxicity Measurement With A 3d Biomimetic Microfluidic Device And Computational Fluid Dynamics Model, Maryam Moarefian, Caroline Jones, Luke Achenie, Danesh Tafti
Biology and Medicine Through Mathematics Conference
No abstract provided.
Investigating Smoke Exposure And Chronic Obstructive Pulmonary Disease (Copd) With A Calibrated Agent Based Model (Abm) Of In Vitro Fibroblast Wound Healing., J Alex Ratti, Angela Reynolds, Rebecca L. Heise
Investigating Smoke Exposure And Chronic Obstructive Pulmonary Disease (Copd) With A Calibrated Agent Based Model (Abm) Of In Vitro Fibroblast Wound Healing., J Alex Ratti, Angela Reynolds, Rebecca L. Heise
Biology and Medicine Through Mathematics Conference
No abstract provided.
Quantifying Effects Of Neutrophil Memory On Migration Patterns Using Microfluidic Platforms And Ode Modeling Of The Mechanistic Molecular Pathways, Brittany P. Boribong, Mark J. Lenzi, Mirjam Sarah Kadelka, Stanca Ciupe, Liwu Li, Caroline N. Jonea
Quantifying Effects Of Neutrophil Memory On Migration Patterns Using Microfluidic Platforms And Ode Modeling Of The Mechanistic Molecular Pathways, Brittany P. Boribong, Mark J. Lenzi, Mirjam Sarah Kadelka, Stanca Ciupe, Liwu Li, Caroline N. Jonea
Biology and Medicine Through Mathematics Conference
No abstract provided.
Modeling Pharmaceutical Inhibition Of Glucose-Stimulated Renin-Angiotensin System In Kidneys, Ashlee N. Ford Versypt, Minu R. Pilvankar, Hui Ling Yong
Modeling Pharmaceutical Inhibition Of Glucose-Stimulated Renin-Angiotensin System In Kidneys, Ashlee N. Ford Versypt, Minu R. Pilvankar, Hui Ling Yong
Biology and Medicine Through Mathematics Conference
No abstract provided.