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Full-Text Articles in Biomedical Engineering and Bioengineering

On The Pursuit Of Developer Happiness: Webcam-Based Eye Tracking And Affect Recognition In The Ide, Tamsin Rogers Jan 2023

On The Pursuit Of Developer Happiness: Webcam-Based Eye Tracking And Affect Recognition In The Ide, Tamsin Rogers

Honors Theses

Recent research highlights the viability of webcam-based eye tracking as a low-cost alternative to dedicated remote eye trackers. Simultaneously, research shows the importance of understanding emotions of software developers, where it was found that emotions have significant effects on productivity, code quality, and team dynamics. In this paper, we present our work towards an integrated eye-tracking and affect recognition tool for use during software development. This combined approach could enhance our understanding of software development by combining information about the code developers are looking at, along with the emotions they experience. The presented tool utilizes an unmodified webcam to capture …


Challenges Of Constructing Entrainment Map For Arbitrary Circadian Models, Yuxuan (Nelson) Wu Jan 2022

Challenges Of Constructing Entrainment Map For Arbitrary Circadian Models, Yuxuan (Nelson) Wu

Honors Theses

The entrainment map, developed by Dr.Diekman and Dr.Bose, is claimed to be a 1-dimensional map that produces a better prediction for phase-locking than methods than the phase response curve for circadian models. In his paper, he constructs the entrainment map for the two-dimensional circadian model, the Novak-Tyson model, and the other two higher-dimensional circadian models. For this thesis, we concentrate on exploring if it is viable to construct the entrainment map for other circadian models that are not included in his paper: the Becker-Weimann model and the Relogio model. In addition, we discuss the challenges of constructing the entrainment map …


Perceptually Improved Medical Image Translations Using Conditional Generative Adversarial Networks, Anurag Vaidya Jan 2021

Perceptually Improved Medical Image Translations Using Conditional Generative Adversarial Networks, Anurag Vaidya

Honors Theses

Magnetic resonance imaging (MRI) can help visualize various brain regions. Typical MRI sequences consist of T1-weighted sequence (favorable for observing large brain structures), T2-weighted sequence (useful for pathology), and T2-FLAIR scan (useful for pathology with suppression of signal from water). While these different scans provide complementary information, acquiring them leads to acquisition times of ~1 hour and an average cost of $2,600, presenting significant barriers. To reduce these costs associated with brain MRIs, we present pTransGAN, a generative adversarial network capable of translating both healthy and unhealthy T1 scans into T2 scans. We show that the addition of non-adversarial …


Heel Down And Toe-Off Time Measured With Ultrasonic Doppler System And Force Plate Sensor, Sabin Timsina May 2020

Heel Down And Toe-Off Time Measured With Ultrasonic Doppler System And Force Plate Sensor, Sabin Timsina

Honors Theses

Collie Box is a medical device that measures the gait parameters of the person walk- ing in front of it. This device uses the Ultrasonic Doppler system to extract the heel-contact and toe-off times of a person walking within the range of 2-10 meters. These times are used to determine the leg’s swing phase and double stance times. The ultrasonic transducer of 10mm diameter is driven at 40kHz. At the time of the heel-contact and toe-off, foot velocity is zero while the torso part of the human body is still in motion. The wide directivity of 10mm diameter ultrasonic transducer …


Investigatin Actin-Myosin Mechanics To Model Heart Disease Using Fluorescence Microscopy And Optical Trapping, Justin Edward Reynolds May 2020

Investigatin Actin-Myosin Mechanics To Model Heart Disease Using Fluorescence Microscopy And Optical Trapping, Justin Edward Reynolds

Honors Theses

Hypertrophic cardiomyopathy (HCM) is a hereditary disease in which the myocardium becomes hypertrophied, making it more difficult for the heart to pump blood. HCM is commonly caused by a mutation in the β-cardiac myosin II heavy chain. Myosin is a motor protein that facilitates muscle contraction by converting chemical energy from ATP hydrolysis into mechanical work and concomitantly moving along actin filaments. Optical tweezers have been used previously to analyze single myosin biophysical properties; however, myosin does not work as a single unit within the heart. Multiple myosin interacts to displace actin filaments and do not have the same properties …