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Full-Text Articles in Biomedical Engineering and Bioengineering
An Investigative Study Into The Relationship Of Bone Morphogenetic Protein Antagonist Expression And Osteocyte Density By Region And Quadrant, Scott C. Mosher
An Investigative Study Into The Relationship Of Bone Morphogenetic Protein Antagonist Expression And Osteocyte Density By Region And Quadrant, Scott C. Mosher
Master's Theses
The role of cytokines and cell behavior and viability with respect to bone remodeling and bone behavior is an exciting area of orthopedic research. The purpose of this study was to investigate the relationships between BMP antagonist expression and osteocyte density, lacunar densities and osteocyte viability in cortical bone. Samples of unloaded tibial bone obtained from six C57Bl/6 mice were immunohistochemically stained for gremlin and noggin expression and also underwent methyl green staining to determine osteocyte presence. Bone sections were divided into four quadrants (cranial, caudal, medial and lateral) and three regions (proximal, mid shaft and distal), followed by analysis …