Open Access. Powered by Scholars. Published by Universities.®

Biomedical Engineering and Bioengineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Other Biomedical Engineering and Bioengineering

University of Arkansas, Fayetteville

2019

Proliferation

Articles 1 - 1 of 1

Full-Text Articles in Biomedical Engineering and Bioengineering

Comparing The Effects Of Fibroblast Growth Factors On Growth Rate Of Human Fibroblast Cell Lines, Tasha Repella May 2019

Comparing The Effects Of Fibroblast Growth Factors On Growth Rate Of Human Fibroblast Cell Lines, Tasha Repella

Biomedical Engineering Undergraduate Honors Theses

Numerous studies have demonstrated the usefulness of growth factors in medium formulations to promote proliferation and viability of human fibroblasts in laboratory settings. However, due to the differences in the source and age of fibroblasts, the ability of growth factors like hFGF1 to promote proliferation varies. Equally difficult is the ability of hFGF1 to promote proliferation of diseased fibroblasts due to complexities associated with specific mitochondrial diseases. In this context, we decided to evaluate the potential for novel hyper stable growth factors super hFGF and hFGF1 (shFGF and hFGF1 respectively), to contribute to proliferation of different normal and diseased fibroblasts. …