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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Quantitative Optical Studies Of Oxidative Stress In Rodent Models Of Eye And Lung Injuries, Zahra Ghanian
Quantitative Optical Studies Of Oxidative Stress In Rodent Models Of Eye And Lung Injuries, Zahra Ghanian
Theses and Dissertations
Optical imaging techniques have emerged as essential tools for reliable assessment of organ structure, biochemistry, and metabolic function. The recognition of metabolic markers for disease diagnosis has rekindled significant interest in the development of optical methods to measure the metabolism of the organ.
The objective of my research was to employ optical imaging tools and to implement signal and image processing techniques capable of quantifying cellular metabolism for the diagnosis of diseases in human organs such as eyes and lungs. To accomplish this goal, three different tools, cryoimager, fluorescent microscope, and optical coherence tomography system were utilized to study the …
Monitoring Changes In Hemodynamics Following Optogenetic Stimulation, Seth Thomas Frye
Monitoring Changes In Hemodynamics Following Optogenetic Stimulation, Seth Thomas Frye
Theses and Dissertations
The brain is composed of billions of neurons, all of which connected through a vast network. After years of study and applications of different technologies and techniques, there are still more questions than answers when it comes to the fundamental functions of the brain. This project aims to provide a new tool which can be used to gain a better understanding of the fundamental mechanisms that govern neurological processes inside the brain. In order for neural networks to operate, blood has to be supplied through neighboring blood vessels. As such, the increase or decrease in the blood supply has been …
Optical Cryoimaging Of Celular Redox In Kidneys From Diabetic Mice, Sepideh Maleki
Optical Cryoimaging Of Celular Redox In Kidneys From Diabetic Mice, Sepideh Maleki
Theses and Dissertations
Diabetic Nephropathy (DN) is the major single cause of end stage renal diseases (ESRD) in the United States. Diabetes is the third leading fatal disorder after cancer and heart disease. It is affecting 8.3% of the residents of the United States, with a total healthcare cost of $174 billion/yr by 2010.
There currently exists a need for a sensitive and specific diagnosis for temporal detection of oxidative stress (OS) in cellular metabolic levels, which plays an early role in the development of DN. The objective of this research is to use a fluorescence optical imaging technique in order to delineate …