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Biomedical Engineering and Bioengineering Commons™
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- Drug delivery (2)
- 5-fluorouracil anti-cancer drug (1)
- Angiogenic growth factors (1)
- Band gap (1)
- Blend NPs (1)
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- Controlled release (1)
- Electrospun poly(ester amide)s (PEAs) fibers (1)
- Fibroblast growth factor-2 (FGF2) (1)
- Fibroblast growth factor-9 (FGF9) (1)
- Floxuridine (1)
- Letrazole (1)
- Magnetic ferrite-encapsulated titania nanotube arrays (1)
- Nanoparticles (1)
- Photoconvesion efficiency (1)
- Photoelctrochemical properties (1)
- Poly(ester amide)s (1)
- Poly(ethyl glyoxylate) (1)
- Polymer drug conjugates (1)
- Self-immolative (1)
- Stimuli responsive polymers (1)
- Therapeutic angiogenesis (1)
- Titania nanotube arrays (1)
Articles 1 - 3 of 3
Full-Text Articles in Biomedical Engineering and Bioengineering
Fabrication And Modification Of Titania Nanotube Arrays For Harvesting Solar Energy And Drug Delivery Applications, Ahmed El Ruby Abdel Rahman Mohamed
Fabrication And Modification Of Titania Nanotube Arrays For Harvesting Solar Energy And Drug Delivery Applications, Ahmed El Ruby Abdel Rahman Mohamed
Electronic Thesis and Dissertation Repository
The fast diminishing of fossil fuels in the near future, as well as the global warming caused by increasing greenhouse gases have motivated the urgent quest to develop advanced materials as cost-effective photoanodes for solar light harvesting and many other photocatalytic applications. Recently, titania nanotube arrays (TNTAs) fabricated by anodization process has attracted great interest due to their excellent properties such as: high surface area, vertically oriented, highly organized, one-dimensional, nanotubular structure, photoactivity, chemical stability and biocompatibility. This unique combination of excellent properties makes TNTAs an excellent photoanode for solar light harvesting. However, the relatively wide band gap energy of …
Controlled Delivery Of Angiogenic And Arteriogenic Growth Factors From Biodegradable Poly(Ester Amide) Electrospun Fibers For Therapeutic Angiogenesis, Somiraa S. Said
Controlled Delivery Of Angiogenic And Arteriogenic Growth Factors From Biodegradable Poly(Ester Amide) Electrospun Fibers For Therapeutic Angiogenesis, Somiraa S. Said
Electronic Thesis and Dissertation Repository
Therapeutic angiogenesis relies on the delivery of exogenous growth factors to stimulate neovessel formation. However, systemic administration of angiogenic factors results in rapid clearance from the site of interest due to their short biological half-life. In this work, we are reporting controlled delivery of a ‘cocktail’ of growth factors, an angiogenic factor −fibroblast growth factor-2 (FGF2), and an arteriogenic factor −fibroblast growth factor-9 (FGF9), from biodegradable poly(ester amide) (PEA) electrospun fibers towards targeting neovascular formation and maturation. FGF2 and FGF9 were dual loaded into PEA fibers using a mixed blend and emulsion electrospinning technique. Matrigel tube formation and Boyden chamber …
Poly(Ester Amide) And Poly(Ethyl Glyoxylate) Nanoparticles For Controlled Drug Release, Amira Mohamed Moustafa
Poly(Ester Amide) And Poly(Ethyl Glyoxylate) Nanoparticles For Controlled Drug Release, Amira Mohamed Moustafa
Electronic Thesis and Dissertation Repository
The objective of this research was to develop polymeric nanoparticles (NPs) having improved drug release properties for drug delivery. Poly(ester amide)s (PEAs) are promising biodegradable polymers. PEA NPs were prepared via emulsification-evaporation and salting-out methods and optimized through by varying different processing parameters. Polymer-model drug conjugates based on PEAs containing L-aspartic acid and rhodamine B were synthesized and used for NP preparation. Release behavior was studied and compared to a control system with physically encapsulated rhodamine B. It was shown that the release of rhodamine B from the covalent system did not show the burst effect and exhibited a slower …