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Full-Text Articles in Biomedical Engineering and Bioengineering
Augmented Image-Guidance For Transcatheter Aortic Valve Implantation, Pencilla Lang
Augmented Image-Guidance For Transcatheter Aortic Valve Implantation, Pencilla Lang
Electronic Thesis and Dissertation Repository
The introduction of transcatheter aortic valve implantation (TAVI), an innovative stent-based technique for delivery of a bioprosthetic valve, has resulted in a paradigm shift in treatment options for elderly patients with aortic stenosis. While there have been major advancements in valve design and access routes, TAVI still relies largely on single-plane fluoroscopy for intraoperative navigation and guidance, which provides only gross imaging of anatomical structures. Inadequate imaging leading to suboptimal valve positioning contributes to many of the early complications experienced by TAVI patients, including valve embolism, coronary ostia obstruction, paravalvular leak, heart block, and secondary nephrotoxicity from contrast use.
A …
Mri-Based Attenuation Correction In Emission Computed Tomography, Harry R. Marshall
Mri-Based Attenuation Correction In Emission Computed Tomography, Harry R. Marshall
Electronic Thesis and Dissertation Repository
The hybridization of magnetic resonance imaging (MRI) with positron emission tomography (PET) or single photon emission computed tomography (SPECT) enables the collection of an assortment of biological data in spatial and temporal register. However, both PET and SPECT are subject to photon attenuation, a process that degrades image quality and precludes quantification. To correct for the effects of attenuation, the spatial distribution of linear attenuation coefficients (μ-coefficients) within and about the patient must be available. Unfortunately, extracting μ-coefficients from MRI is non-trivial. In this thesis, I explore the problem of MRI-based attenuation correction (AC) in emission tomography.
In particular, I …