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Full-Text Articles in Biomedical Engineering and Bioengineering
Parameter Estimation Of The Arterial System, James Charles Carter Ii
Parameter Estimation Of The Arterial System, James Charles Carter Ii
Mechanical & Aerospace Engineering Theses & Dissertations
There are a number of disorders that originate from or involve faulty operation of the cardiovascular system. Diseases such as atherosclerosis, diabetes and hypertension can have a debilitating effect on blood flow. This makes the tools for simulating the effects of such diseases on blood flow important. Measures, such as pulse wave velocity, that are generated by models of the cardiovascular system can be important indicators of cardiac health. Although physically measurable, obtaining some parameters comes with a high cost and discomfort to the patient. Models can provide an assessment of many important parameters. The purpose of this project was …
Caffeine Model Identification For Vigilance Performance Prediction, Chun-Hui Huang
Caffeine Model Identification For Vigilance Performance Prediction, Chun-Hui Huang
Mechanical & Aerospace Engineering Theses & Dissertations
The pharmacodynamics and pharmacokinetics of caffeine have been well characterized. In this study, a caffeine dynamic model is developed to describe its pharmacodynamic effects on vigilance performance. Validated biomathematical models developed to address both individual and group fatigue and alertness in a non-laboratory setting represent a tremendous commercial opportunity. First, a test data set with caffeine effects isolated from circadian and homeostatic effects is created. Then a modeling approach for input and output effects is developed and different model structures for the caffeine effects are considered. Observer/Kalman filter Identification (OKID) algorithm is proposed and developed to identify the caffeine model …