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Full-Text Articles in Biomedical Engineering and Bioengineering

Towards Supervised Autonomous Task Completion Using An In Vivo Surgical Robot, Jason J. Dumpert Oct 2009

Towards Supervised Autonomous Task Completion Using An In Vivo Surgical Robot, Jason J. Dumpert

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Laparoscopy is a minimally invasive alternative to traditional abdominal surgery. Unlike traditional surgery, a laparoscopic procedure can be completed using small incisions. The use of these small incision results in reduced pain to the patient, shorter recovery times, and less trauma to skin, muscle and other tissues. However, these benefits to the patient are offset by the increased difficulty to the surgeon performing the procedure. These difficulties include reduced dexterity, reduced perception, and longer procedure times. The use of small in vivo robotic devices in minimally invasive surgery is one possible solution to these problems. The movement of these devices …


Influence Of Towing Force Magnitude On The Kinematics Of Supramaximal Sprinting, David A. Clark, Seth Kuhlman, Michelle B. Sabick, Ronald P. Pfeiffer, Nicole A. Knigge Jul 2009

Influence Of Towing Force Magnitude On The Kinematics Of Supramaximal Sprinting, David A. Clark, Seth Kuhlman, Michelle B. Sabick, Ronald P. Pfeiffer, Nicole A. Knigge

Mechanical and Biomedical Engineering Faculty Publications and Presentations

The purpose of this study was to determine the influence of towing force magnitude on the kinematics of supramaximal sprinting. Ten high school and collegiate aged track and field athletes ran 60m maximal sprints under 5 different conditions: non-towed (NT), Tow A (2.0% body weight), Tow B (2.8%BW), Tow C (3.8%BW), and Tow D (4.7%BW). Three-dimensional kinematics of a 4-segment model of the right side of the body were collected starting at the 35m point of the trial. Significant differences were observed in stride length (SL) and horizontal velocity of the center of mass (VH) during Tow C and Tow …


A Real-Time, 3-D Musculoskeletal Model For Dynamic Simulation Of Arm Movements, Edward K. Chadwick, Dimitra Blana, Antonie J. Van Den Bogert, Robert F. Kirsch Apr 2009

A Real-Time, 3-D Musculoskeletal Model For Dynamic Simulation Of Arm Movements, Edward K. Chadwick, Dimitra Blana, Antonie J. Van Den Bogert, Robert F. Kirsch

Mechanical Engineering Faculty Publications

Neuroprostheses can be used to restore movement of the upper limb in individuals with high-level spinal cord injury. Development and evaluation of command and control schemes for such devices typically require real-time, ldquopatient-in-the-looprdquo experimentation. A real-time, 3-D, musculoskeletal model of the upper limb has been developed for use in a simulation environment to allow such testing to be carried out noninvasively. The model provides real-time feedback of human arm dynamics that can be displayed to the user in a virtual reality environment. The model has a 3-DOF glenohumeral joint as well as elbow flexion/extension and pronation/supination and contains 22 muscles …


The Relationships Between Muscle, External, Internal And Joint Mechanical Work During Normal Walking, Kotaro Sasaki, Richard R. Neptune, Steven A. Kautz Mar 2009

The Relationships Between Muscle, External, Internal And Joint Mechanical Work During Normal Walking, Kotaro Sasaki, Richard R. Neptune, Steven A. Kautz

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Muscle mechanical work is an important biomechanical quantity in human movement analyses and has been estimated using different quantities including external, internal and joint work. The goal of this study was to investigate the relationships between these traditionally used estimates of mechanical work in human walking and to assess whether they can be used as accurate estimates of musculotendon and/or muscle fiber work. A muscle-actuated forward dynamics walking simulation was generated to quantify each of the mechanical work measures. Total joint work (i.e. the time integral of absolute joint power over a full gait cycle) was found to underestimate total …


Rapid-Response Urban Cfd Simulations Using A Gpu Computing Paradigm On Desktop Supercomputers, Inanc Senocak, Julien C. Thibault, Matthew Caylor Jan 2009

Rapid-Response Urban Cfd Simulations Using A Gpu Computing Paradigm On Desktop Supercomputers, Inanc Senocak, Julien C. Thibault, Matthew Caylor

Mechanical and Biomedical Engineering Faculty Publications and Presentations

In the event of chemical or biological (CB) agent attacks or accidents, first-responders need hazard prediction data to launch effective emergency response action. Accurate and timely knowledge of the wind fields in urban areas is critically important to identify and project the extent of CB agent dispersion to determine the hazard-zone. In their 2008 report (GAO-08-180), U.S. Government Accountability Office has reported that first responders are limited in their ability to detect and model hazardous releases in urban environments. The current set of modeling tools for contaminant dispersion in urban environments rely on empirical assumptions with diagnostic equations (Wang et …


A Shooting Algorithm For Complex Immunodominance Control Problems, Xiaopeng Zhao, R Yang, M Zhang Jan 2009

A Shooting Algorithm For Complex Immunodominance Control Problems, Xiaopeng Zhao, R Yang, M Zhang

Faculty Publications and Other Works -- Mechanical, Aerospace and Biomedical Engineering

Although T cells are able to recognize a wide variety of target peptides, they are often strongly focused on a few of the peptides and leave the rest of them unattended. This phenomenon of strongly biased immune response is known as immunodominance. Mathematically, an immunodominance problem can be formulated using optimal control principles as a two-point boundary-value problem. The solution of this problem is challenging especially when the control variables are bounded. In this work, we develop a numerical algorithm based on the shooting technique for bounded optimal control problems. The algorithm is applied to a group of immunodominance problems. …


Therapeutic Ultrasound Angioplasty: The Risk Of Arterial Perforation. An In Vitro Study, Mark Wylie, Garrett Mcguinness, Graham Gavin Jan 2009

Therapeutic Ultrasound Angioplasty: The Risk Of Arterial Perforation. An In Vitro Study, Mark Wylie, Garrett Mcguinness, Graham Gavin

Conference Papers

The use of therapeutic ultrasound delivered via small diameter wire waveguides may represent an emerging minimally invasive approach in the treatment of chronic total occlusions (CTOs), calcified and fibrous plaques. The distal-tip mechanical vibrations (typically 0-210 μm peak-to-peak) have been reported to debulk rigid calcified and fibrous tissues while healthy elastic arterial tissue remains largely unaffected. The risk of arterial (healthy tissue) perforation with energized waveguides is not fully understood. An ultrasonic apparatus capable of delivering a range of wire waveguide distal-tip displacements, up to 80 μm peak-to-peak (p-p), at an operational frequency of 22.5 KHz (+/- 6%) has been …


Ultrasonic Angioplasty: Assessing The Risk Of Arterial Perforation, Mark Wylie, Garrett Mcguinness, Graham Gavin Jan 2009

Ultrasonic Angioplasty: Assessing The Risk Of Arterial Perforation, Mark Wylie, Garrett Mcguinness, Graham Gavin

Conference Papers

Atherosclerosis is a cardiovascular disease that effects large and medium muscular arteries (such as coronary and iliac) and also large elastic arteries (such as aorta) [1]. It causes thickening of the arterial wall and over time can result in a completely blocked artery or chronic total occlusion (CTO). While the majority of atherosclerotic lesions can be attempted by typical Percutaneous Transluminal Coronary Angioplasty (PTCA) such as balloon and stent implantation, calcified CTOs are often problematic as they do not lend themselves to be accessed by the guidewire which is required to implant the balloon and stent. Excessive guidewire pushing force …


Cuda Implementation Of A Navier-Stokes Solver On Multi-Gpu Desktop Platforms For Incompressible Flows, Julien C. Thibault, Inanc Senocak Jan 2009

Cuda Implementation Of A Navier-Stokes Solver On Multi-Gpu Desktop Platforms For Incompressible Flows, Julien C. Thibault, Inanc Senocak

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Graphics processor units (GPU) that are traditionally designed for graphics rendering have emerged as massively-parallel "co-processors" to the central processing unit (CPU). Small-footprint desktop supercomputers with hundreds of cores that can deliver teraflops peak performance at the price of conventional workstations have been realized. A computational fluid dynamics (CFD) simulation capability with rapid computational turnaround time has the potential to transform engineering analysis and design optimization procedures. We describe the implementation of a Navier-Stokes solver for incompressible fluid flow using desktop platforms equipped with multi-GPUs. Specifically, NVIDIA’s Compute Unified Device Architecture (CUDA) programming model is used to implement the discretized …