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Full-Text Articles in Biomedical Engineering and Bioengineering

Evaluation Of Far-Side Occupant Safety Based On Numerical Modeling, Syed Akhtar Imam Jan 2020

Evaluation Of Far-Side Occupant Safety Based On Numerical Modeling, Syed Akhtar Imam

Wayne State University Dissertations

The objective of this study was to augment the knowledge of the far-side occupant injury biomechanics in side impact vehicle crashes. Most research studies conducted to investigate the far-side occupant injuries are through the field crash data for a better understanding of human impact responses, injury mechanisms, and injury tolerance levels. The data obtained from field data is also used in the development of injury mitigation technologies, such as safety belts, airbags, etc. A field data represents the injury outcome of an automotive crash, but it doesn’t leave behind enough information for in-depth knowledge. The use of cadaver is the …


Biomechanics Of Concussion: The Importance Of Neck Tension, Ron Jadischke Jan 2017

Biomechanics Of Concussion: The Importance Of Neck Tension, Ron Jadischke

Wayne State University Dissertations

Linear and angular velocity and acceleration of the head are typically correlated to concussion. Despite improvements in helmet performance to reduce accelerations, a corresponding reduction in the incidence of concussion has not occurred (National Football League [NFL] 1996 – present).

There is compelling research that forces on and deformation to the brain stem are related to concussion. The brain stem is the center of control for respiration, blood pressure and heart rate and is the root of most cranial nerves. Injury to the brain stem is consistent with most symptoms of concussion reported in the National Football League and the …


Development Of A Finite Element Pelvis And Lower Extremity Model With Growth Plates For Pediatric Pedestrian Protection, Ming Shen Jan 2017

Development Of A Finite Element Pelvis And Lower Extremity Model With Growth Plates For Pediatric Pedestrian Protection, Ming Shen

Wayne State University Dissertations

Finite element (FE) model is a useful tool frequently used for investigating the injury mechanisms and designing protection countermeasures. At present, no 10 years old (YO) pedestrian FE model has been developed from appropriate anthropometries and validated against limitedly available impact response data. A 10 YO child FE pelvis and lower extremities (PLEX) model was established to fill the gap of lacking such models in this age group. The baseline model was validated against available pediatric postmortem human subjects (PMHS) test data and additional scaled adult data, then the PLEX model was integrated to build a whole-body FE model representing …


High-Performance Accelerometer Based On Asymmetric Gapped Cantilevers For Physiological Acoustic Sensing, Yating Hu Jan 2014

High-Performance Accelerometer Based On Asymmetric Gapped Cantilevers For Physiological Acoustic Sensing, Yating Hu

Wayne State University Dissertations

Continuous or mobile monitoring of physiological sounds is expected to play important role in the emerging mobile healthcare field. Because of the miniature size, low cost, and easy installation, accelerometer is an excellent choice for continuous physiological acoustic signal monitoring. However, in order to capture the detailed information in the physiological signals for clinical diagnostic purpose, there are more demanding requirements on the sensitivity/noise performance of accelerometers. In this thesis, a unique piezoelectric accelerometer based on the asymmetric gapped cantilever which exhibits significantly improved sensitivity is extensively studied. A meso-scale prototype is developed for capturing the high quality cardio and …


Induced Damping And Its Relationship To Beneficial Energy Harvesting In Dielectric Elastomers With Application To Walking, Heather L. Lai Jan 2013

Induced Damping And Its Relationship To Beneficial Energy Harvesting In Dielectric Elastomers With Application To Walking, Heather L. Lai

Wayne State University Dissertations

This dissertation presents a novel, interdisciplinary research which addresses the potential of applying soft polymeric materials to strategically harvest biomechanical energy in a beneficial manner for use as a viable, low power source for on-board electronics. Of particular interest are electroactive polymers (EAP), which unlike other types of electromechanical smart materials such as piezoelectric ceramics, which are often brittle, have low elastic modulus and can exhibit large strains without substantial stress generations. One type of EAP, the dielectric elastomer (DE), which utilizes electrostatic forces built up across the dielectric polymer to convert between electrical and mechanical energy, is employed in …


Contact Pressure Distribution Of Osteochondral Defects Of The Knee: Effects Of Non-Vertical Walls, Scott Ensminger Jan 2012

Contact Pressure Distribution Of Osteochondral Defects Of The Knee: Effects Of Non-Vertical Walls, Scott Ensminger

Wayne State University Theses

Purpose: To examine the relationship between well-shouldered osteochondral defects and

defects of different geometries by studying their effects on rim stress concentration and

load redistribution in the human knee.

Methods: Ten fresh-frozen cadaveric knees were mounted at 30° of flexion in a materials

testing machine. Digital electronic pressure sensors were placed in the medial and lateral

compartments of the knee. Dynamic pressure readings were recorded throughout the

loading and holding phases as each knee was loaded to 700N and held for 5 seconds.

Artificial defects were created in each knee to simulate well-shouldered defects and

beveled-defects. Loading was repeated for …


Numerical Simulation And Experimentation Of Pulsatile Flows In Axisymmetric Arterial Models, Tadesse Gebreegziabher Jan 2012

Numerical Simulation And Experimentation Of Pulsatile Flows In Axisymmetric Arterial Models, Tadesse Gebreegziabher

Wayne State University Dissertations

ABSTRACT

NUMERICAL SIMULATION AND EXPERIMENTATION OF PULSATILE FLOWS IN AXISYMMETRIC ARTERIAL MODELS

by

TADESSE GEBREEGZIABHER

December 2011

Co-advisors: 1. Dr. Emmanuel Ayorinde 2. Dr. Trilochan Singh

Major: Mechanical Engineering

Degree: Doctor of Philosophy

The primary motivation for this dissertation is the fluid flow and structural response to unsteady blood flow in the human body. The research work is a synergistic merging of numerical simulation and experimentation. For the experiments, an all-encompassing, highly flexible experimental apparatus was designed and fabricated to facilitate a wide range of operating conditions, the range of which was chosen to accommodate mammalian cardiovascular system for both …


Locating And Extracting Acoustic And Neural Signals, Na Zhu Jan 2011

Locating And Extracting Acoustic And Neural Signals, Na Zhu

Wayne State University Dissertations

This dissertation presents innovate methodologies for locating, extracting, and separating multiple incoherent sound sources in three-dimensional (3D) space; and applications of the time reversal (TR) algorithm to pinpoint the hyper active neural activities inside the brain auditory structure that are correlated to the tinnitus pathology. Specifically, an acoustic modeling based method is developed for locating arbitrary and incoherent sound sources in 3D space in real time by using a minimal number of microphones, and the Point Source Separation (PSS) method is developed for extracting target signals from directly measured mixed signals. Combining these two approaches leads to a novel technology …


Finite Element Reconstruction Of Real World Aortic Injury In Near-Side Lateral Automotive Crashes With Conceptual Countermeasures, Aditya Neelakanta Belwadi Jan 2011

Finite Element Reconstruction Of Real World Aortic Injury In Near-Side Lateral Automotive Crashes With Conceptual Countermeasures, Aditya Neelakanta Belwadi

Wayne State University Dissertations

Traumatic rupture of the aorta (TRA) remains the second most common cause of death associated with motor vehicle crashes after brain injury. On an average, nearly 8,000 people die annually in the United States due to blunt injury to the aorta. It is observed that more than 80% of occupants who suffer an aortic injury die at the scene due to exsanguination into the chest. With the advent of more accurate and established human body finite element (FE) models, FE crash reconstruction methods may become a valuable tool when assessing crash scenarios and occupant injury mechanisms.

The current study is …