Biomedical Engineering and Bioengineering Commons^™

Synthesis Of Bone Scaffold For Pediatric Bone Defects Using 3d Printing, Amy M. Ramos-Homs

2022 MME Undergraduate Research Symposium

Pediatric bone defects, requiring surgical interventions and implants, include malignant and nonmalignant bone tumors and trauma fractures. Malignant bone tumors (MBT), such as Osteosarcoma and Ewing sarcoma, are aggressive primary cancers that affect growing adolescent bones (10- to 19-year-olds) and require complex reconstruction due to large bone excision during surgical interventions. Pediatric bone fractures requiring surgical interventions peak in 10- to 14-year-olds and are a major public health concern in the US with an impact on patients, parents, and healthcare costs of approx. 350 billion. These diseases require bone tissue replacement in changing bones.

Bone reconstruction and medical implant design …