Biomedical Engineering and Bioengineering Commons^™

Development Of A Pneumatically Controllable Microdroplet Generator With Electrical Sensing, Gnanesh Nagesh

Electronic Theses and Dissertations

Microfluidic droplet generation is popular in lab-on-a-chip based biochemical analysis because it can provide precise and high throughput fluids in the form of small droplets. This thesis presents a T-junction microdroplet generator with pneumatic actuation for regulating droplet size and a capacitance-based sensor with real-time sensing capability for characterizing droplet composition and size. The multi-layer device developed in this thesis is compatible with rapid manufacturing using a desktop-based laser cutter to fabricate the fluidic and pneumatic layers. A finite element based numerical model was developed to predict the best operating and geometric parameters for droplet generation. It was revealed that …

Dynamic Behavior And Interactions Of Ferrofluid Droplets Under Magnetic Fields In Low Reynolds Number Flows, Md Rifat Hassan

Doctoral Dissertations

Digital microfluidics in combination with emulsion microfluidics are crucial building blocks of droplet-based microfluidics, which are prevalent in a wide variety of industrial and biomedical applications, including polymer processing, food production, drug delivery, inkjet printing, and cell-based assays. Therefore, understanding the dynamics and interactions of droplets as well as the interactions between the droplets and solid surfaces are of great importance in order to improve the performance or product in these applications.

Recently, several studies in the literature have demonstrated the potential of magnetic fields in controlling the behavior of droplets in microscale; however, the fundamental mechanism behind the interesting …