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Estimation Of Arterial Wall Parameters Via Model-Based Analysis Of Noninvasively Measured Arterial Pulse Signals, Dan Wang
Mechanical & Aerospace Engineering Theses & Dissertations
This dissertation presents a model-based method for estimating arterial wall parameters from noninvasively measured arterial pulse signals via a microfluidic-based tactile sensor. The sensor entails a polydimethylsiloxane (PDMS) microstructure embedded with 5×1 transducer array built on Pyrex/Polyethylene terephthalate (PET) substrate. The arterial pulse causes a time-varying deflection on the top of the PDMS microstructure, which registers as a resistance change by the transducer at the site of the artery.
Owing to the time-harmonic nature of its radial motion, the arterial wall is modeled as a second-order dynamic system. By combining this dynamic model with a hemodynamic model of blood flow, …